Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05039463

Acronym

ISPAG

Enrollment

100

Registered

2021-09-09

Start date

2021-08-16

Completion date

2026-06-01

Last updated

2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyaluronic Acid, Knee Osteoarthritis, Platelet Rich Plasma

Keywords

platelet rich plasma, hyaluronic acid, Knee Osteoarthritis

Brief summary

The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data. In fact, the injection protocols are very heterogeneous in terms of preparation method, the presence or not of leukocytes, the number of centrifugations, the volume injected, the ultrasound guidance, which makes it difficult to analyze the literature. The investigator objective is therefore to evaluate the effectiveness of combined injections of PRP and hyaluronic acid.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age : \> 18 years old * Patients benefiting, in the context of knee osteoarthritis, from viscosupplementation alone or from two injections of PRP, in combination with HA, at the Amiens University Hospital.

Exclusion criteria

* Patient refusal to use the data * Language barrier * Age less than 18 years old.

Design outcomes

Primary

Measure	Time frame
change of the visual analogue scale (VAS) from the "PRP + HA" group on the "HA alone" group	up to one year

Countries

France

Contacts

CONTACTLAURE LE MONNIER, MD

lemonnier.laure@chu-amiens.fr03 22 66 82 50

Outcome results