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Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery

Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05038111
Enrollment
81
Registered
2021-09-08
Start date
2021-03-11
Completion date
2021-03-25
Last updated
2021-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hospital Length of Stay, Mechanical Ventilation, Minimally Invasive Cardiac Surgery

Keywords

mechanical ventilation, hospital length of stay, dexmedetomidine, Minimally Invasive Cardiac Surgery

Brief summary

The concept of enhanced recovery after surgery (ERAS) is utilizing in multiple specialties widely. Early tracheal extubation is one of the components of ERAS that enhances postoperative recovery and reduces the length of stay in intensive care unit (ICU).Dexmedetomidine is a highly selective, shorter-acting α2-adrenergic receptor agonist that has both analgesic and sedativeeffects.It was associated with decreased mortality, time to extubation, and hospital length of stay in cardiac surgical patients according to previous studies.The purpose of this study was to investigate the effect of perioperative dexmedetomidine on patients undergoing minimally invasive cardiac surgery(MICS) who were early extubated after surgery.

Interventions

DRUGDexmedetomidine

perioperative dexmedetomidine infusion

Sponsors

Far Eastern Memorial Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 99 Years
Healthy volunteers
No

Inclusion criteria

* Patients undergone minimal invasive off-pump coronary artery bypass graft (CABG), valvular surgery or combined procedures at Far Eastern Memorial Hospital, New Taipei City, Taiwan between January 1, 2020 and August 31, 2020. * Age above 20 y/o

Exclusion criteria

* Emergency surgery * Postoperative mechanical ventilation more than 6 hours * Extubated in the operating room

Design outcomes

Primary

MeasureTime frameDescription
postoperative mechanical ventilation durationup to 1 weekfrom the time the patient arrived at the ICU until extubation
ICU and hospital length of staythrough admission, up to 1 month

Secondary

MeasureTime frameDescription
postoperative complicationsaccording to ICD 10 on medical record, daily to discharge, up to 1 monthatrial fibrillation, bradyarrhythmia, myocardial infarction, cerebrovascular accident, acute renal failure and delirium

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026