Chronic Obstructive Pulmonary Disease
Conditions
Keywords
ultrasonography, diaphragm, COPD, Fayoum
Brief summary
The study of the diaphragm is an important point in the assessment of COPD patients. Ultrasonographic evaluation of the diaphragm is considered a simple, non-invasive, available bedside technique. Ultrasonography can be used for evaluation of the site, structure, and motion of the diaphragm, assessment of excursion, and thickness. The aim of the study is ultrasonographic assessment of the diaphragm in COPD patients and its relation to disease severity
Detailed description
The study was conducted on eighty patients, forty COPD patients who were diagnosed and classified into four groups according as following: The first group: included 10 patients with a mild stage. The second group: included 10 patients with a moderate stage. The third group: included 10 patients with a severe stage. The fourth group: included 10 patients with a very severe stage. The study also included forty healthy individuals of the same age and sex as COPD patients. All participants gave their informed consent for inclusion before sharing in the study. Every person was submitted to: Full medical history, Clinical examination,Chest x-ray, spirometry and ultrasonographic assessment of diaphragm function (thickness and excursion)
Interventions
DEVICEultrasonography
ultrasound assessment of diaphragm function
Sponsors
Enas Sayed Farhat
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
40 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* • Stable COPD patients aged more than 40 years who were diagnosed and classified into four groups of severity according to GOLD 2020. * Age and sex-matched healthy controls
Exclusion criteria
* • Patient with a known neuromuscular disorder. * Patient with known anatomical malformation of the diaphragm. * Post abdominal or thoracic surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure diaphragmatic thickness by ultrasound | 1 year study | measure diaphragmatic thickness at total lung capacity and residual volume in millimetres to calculate diaphragm thickness fraction |
| measure diaphragm excursion by ultrasound | 1 year study | measure diaphragm excursion in centimetres at zone of apposition |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| spirometry assessment | 1 year study | value of forced expiratory volume in first second is assessed as a percentage of normal by spirometry to assess disease severity |
| questionnaires | 1 year study | ( modified medical research council and chronic obstructive pulmonary disease assessment test) to detect severity of the disease |
Countries
Egypt
Outcome results
None listed