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The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05033665
Acronym
WEXMO
Enrollment
217
Registered
2021-09-05
Start date
2021-05-26
Completion date
2023-04-26
Last updated
2023-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dehydration, Mood

Brief summary

Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis, characterized by elevated vasopressin, lower urinary output, and concentrated urine without any measurable changes in total body water. It is well established that dehydration (water deficit) decreases exercise performance and worsens mood, mainly in women. However, the impact of increased water intake in underhydrated individuals on their exercise capacity and mood is not known. The aim of the proposed study is to investigate the impact of increased water intake in underhydrated individuals on aerobic exercise performance and mood in both women and men.

Interventions

BEHAVIORALIncrease water consumption

The underhydrated individuals will be instructed to increase their water intake for one week in order to meet the following two criteria: a) urinate at least 7 times per day and b) have straw-like color urine. A 2-mile run will be completed before and after the 7-day intervention.

BEHAVIORALMaintain adequate water consumption

The subjects that are classified as euhydrated will be asked to maintain high water intake for one week to ensure proper hydration. A 2-mile run will be completed before and after the 7-day intervention.

Sponsors

Arizona State University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy adults * Residence in Arizona

Exclusion criteria

* Use of diuretics * Use of anti-depressive medication * Current pregnancy or lactation * Current use of injectable insulin * Diagnosed with irritable bowel syndrome * Do not pass the Physical Activity Readiness Questionnaire for Everyone (PAR-Q) screening

Design outcomes

Primary

MeasureTime frameDescription
2-mile run-time (min)Day 1
MoodPre-trial on day 1Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)
Urine osmolality (mmol/kg)4 - 8 PM on day 0
Urine specific gravity4 - 8 PM on day 0

Secondary

MeasureTime frameDescription
Urine color4 - 8 PM on day 0Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).
Thirst perception4 - 8 PM on day 0175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026