Stone, Kidney, Urolithiasis, Urologic Diseases
Conditions
Brief summary
To evaluate the efficacy and stone free rate of placebo versus tamsulosin as medical expulsive therapy post-SWL in patients with renal stone less than 20 mm
Interventions
DRUGTamsulosin
Tamsulosin 0.4 mg once daily
DRUGPlacebo
Placebo once daily
Sponsors
Mansoura University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Renal stone ≤ 20 mm. * Lower calyceal stone ≤ 15 mm
Exclusion criteria
* Women with known or suspected pregnancy or breastfeeding. * History of alpa-blockers (more than 7 days prior to study participation) * History of ureteral stricture * Multiple (that is more than 2) stones * Stone in solitary kidney (either anatomically or functionally). * Presence of urinary sepsis. * Estimated glomerular filtration rate \< 30 ml/min * Contraindication or allergy to tamsulosin
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stone free rate defined as patient free of any stone residual | at 3 months | assessed by Non-contrast Computed Tomography of Urinary Tract (NCCT-UT) |
Countries
Egypt
Outcome results
None listed