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The Role of Hypospadias Objective Scoring Evaluation (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair

The Role of Hypospadias Objective Scoring Evaluation (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05032222
Enrollment
105
Registered
2021-09-02
Start date
2021-05-01
Completion date
2023-05-01
Last updated
2021-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypospadias

Brief summary

Hypospadias is a common anomaly of the male genitalia affecting 0.4-8.2 of 1000 live male babies and varies considerably in severity. The position of the urethral meatus can be classified as anterior or distal (glandular, coronal, or subcoronal; 60-65% of cases), middle (midpenile; 20-30% of cases), or posterior or proximal (posterior penile, penoscrotal, scrotal, or perineal; 10-15% of cases). The subcoronal position is the most common. Most cases are mild and surgical correction is undertaken mostly for cosmetic reasons at the request of the parents or on advice of the pediatrician or surgeon. Functional success of hypospadias repair depends on the creation of a uniform and adequate caliber urethra up to the meatus. Accordingly, meatal stenosis and urethral stricture are the important complications of surgery, others include urethrocutaneous fistula, diverticula, skin flap necrosis and persistent chordee. Although functional assessment of the repair is possible by observation of the urinary stream and voiding cystourethrography, uroflowmetry is considered to be a more objective tool, especially for the detection of a subclinical urethral stricture. Reports of the results of hypospadias surgery commonly focus on the cosmetic results and incidence of obvious complications, as urethrocutaneous fistulas, and symptomatic urethral Strictures. Few have emphasized the role of uroflowmetry in the postoperative evaluation of children with hypospadias to detect asymptomatic strictures and, despite the simplicity and non-invasive nature of this test, it has not become standard or widely accepted. We evaluate AUUH experience by use of 'hypospadias objective scoring evaluation' HOSE and uroflowmetry after hypospadias repair. The HOSE is a validated scoring system that incorporates the evaluation of meatal location and shape, urinary stream, straightness of erection, presence and complexity of urethral fistula. The minimum total score is 5, and the maximum total score is 16. The point score is graded as either acceptable or not.

Interventions

Diagnostic test

Sponsors

Mohammad Alaa Ezzat
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
MALE
Age
6 Months to 18 Years
Healthy volunteers
Yes

Inclusion criteria

1. More than six months after last hypospadias repair. 2. Toilet trained children. 3. Patients less than 18 years old. 4. Successful repair of hypospadias with HOSE score more than 10 decided by one of the experts in pediatric urology.

Exclusion criteria

1. Patient not welling to participate in our study. 2. Within six months of last hypospadias repair. 3. Patient had urethral intervention within 3 months. 4. Children with any associated neurological or urological abnormality related to the bladder, which could potentially affect flow pattern.

Design outcomes

Primary

MeasureTime frameDescription
Number of patients show Change of the maximum flow rate, average flow rate (Qav), total voided volume, PMR and voiding time from normal values.Within 5 years post operativeNumber of patients show Change of the maximum flow rate, average flow rate (Qav), total voided volume, PMR and voiding time from normal values.
Number of patients in each Type of the curve of the uroflowmetry.Within 5 years postoperativeNumber of patients in each Type of the curve of the uroflowmetry.
Finding correlation between the results of uroflowmetry and HOSE score.Within 5 years postoperativeFinding correlation between the results of uroflowmetry and HOSE score.

Countries

Egypt

Contacts

Primary ContactMohamad A Ezzat, Resident
mohamed.20134296@med.au.edu.eg+201125035035

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026