Meibomian Gland Dysfunction
Conditions
Keywords
thermal massage, corneal aberrations, physical therapy
Brief summary
To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.
Detailed description
62 MGD patients treated with meibomian gland thermal massage once a week for 3 to 4 weeks were recruited.The Ocular Surface Disease Index questionnaire; tear film assessment encompassing tear meniscus height and non-invasive keratograph breakup time ; meibography score,corneal fluorescein staining; the Schirmer I test ; expressible meibomian gland, and quality ,anterior and total corneal aberrations were evaluated before and after treatment.
Interventions
None listed
Sponsors
Wenzhou Medical University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* tear break-up time (BUT) ≤10 seconds or Schirmer I test (SIT) ≤10 mm, the presence of dry eye symptoms, and fluorescein staining (FL) score \<3 points and at least one lid margin abnormality and poor meibomian gland expressibility
Exclusion criteria
* eyelid structure abnormal(Entropion , ectropion); * having received any other treatment for MGD within three months * history of ocular surgery * contact lens use * ocular infection * any type of corneal scarring
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| corneal aberration corneal aberrations | baseline and 1 week after treatment | Corneal aberrations were measured with a Pentacam。 The anterior corneal wavefront aberration was expanded with normalized Zernike polynomials.The corneal aberration from 3rd to 6th order were recorded as the root mean square (RMS) for analysis. |
Countries
China
Outcome results
None listed