Endoscopic Repair of Frontal Sinus CSF Leak

Outcome of the Endoscopic Repair of Frontal Sinus Cerebrospinal Fluid Leak

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05024643

Enrollment

Registered

2021-08-27

Start date

2015-05-01

Completion date

2021-04-01

Last updated

2021-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CSF Leakage

Brief summary

This retrospective study was conducted on patients with frontal sinus leaks came to ENT departments of Al-Azhar University Hospital, New Damietta, Egypt, for a period of five years.

Detailed description

All patients in this study were evaluated during the follow-up period. Patients' age, sex, occupation, residence, and telephone number were recorded for each participant for demographic purposes. General and local examinations were also performed preoperatively as usual. Medical history, surgical approach, leakage site, complications, reconstruction technique, and follow-up were recorded. All cases were treated by endonasal endoscopy * Complete sphenoethmoidectomy. * Draf type IIa, IIb, and III according to defect location. * Defect less than 3 mm closed by a plug of fat and facia lata or middle turbinate mucosa. * Defect more than 3 mm closed by underlying facia lata, underlying cartilage, and overlay facia lata.

Interventions

PROCEDUREEndonasal endoscopy

Complete sphenoethmoidectomy; Draf type IIa, IIb, and III according to defect location. Defect less than 3 mm closed by a plug of fat and facia lata or middle turbinate mucosa. Defect more than 3 mm closed by underlying facia lata, underlying cartilage, and overlay facia lata.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

10 Years to 80 Years

Inclusion criteria

* patients who underwent endoscopic frontal sinus repair. Traumatic or spontaneous patients with a CSF leak at a minimum of six months not responding to conservative measures were included.

Exclusion criteria

* Known malignancy or patients with frontal leak due to extensive tumor resection or intracranial injury

Design outcomes

Primary

Measure	Time frame	Description
Successful treatment	1 year	Intracranial tension from 7-15 mmHg, No leakage, No complications

Secondary

Measure	Time frame	Description
Complications	1 week	Elevated intracranial tension, more than 15 mmHg, Fever, more than 37.5 degree, Meningitis

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026