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Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

Effect of Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

Status
UNKNOWN
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05021315
Enrollment
800
Registered
2021-08-25
Start date
2021-09-15
Completion date
2022-10-15
Last updated
2022-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section Complications, Postoperative Infection, Vaginal Infection

Brief summary

The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection Research questions: Does vaginal cleaning using povidone iodine before cesarean section has effect on reduction of postoperative wound infection??

Interventions

50 women who received preoperative vaginal cleansing with 10% povidone iodine.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 38 Years
Healthy volunteers
No

Inclusion criteria

* 1\. Pregnant women who are 37 weeks gestation or more scheduled for elective cesarean section or those in labor with a limited number of vaginal examinations less than 5 times preoperatively. 2\. Pregnant women who are 37 weeks gestation or more with rupture of membranes but duration less than 24 hours 3\. Women consenting to be included in the study.

Exclusion criteria

1. Abnormally invasive placenta and placenta previa. 2. Intra-partum fever. 3. Prolonged rupture of membranes more than 24 hours 4. History of exposure to radiation treatment for cancer. 5. History of Gynecological infections (PID). 6. History of abdominal infections, e.g., peritonitis. 7. Debilitating diseases like Diabetes mellitus, Thyroid disorders, Cushing disease, abdominal malignancy. 8. Obesity is defined as pregnant BMI \>30 kg/m2. 9. History of wound infection or burst abdomen. 10. History suggestive of massive bleeding during previous cesarean section. 11. allergy to iodine-containing solutions 12. Pregnant women with severe anemia defined as Hb \<7 g/dl. 13. Cases with intra-abdominal drain deployment are discarded. 14. Obstructed labor with numerous vaginal examinations.

Design outcomes

Primary

MeasureTime frameDescription
Postoperative wound complication1 weekAny sign of infection as redness, hotness and tenderness as well as pyrexia occurance in wound postoperative

Countries

Egypt

Contacts

Primary ContactMohammed A Taymour, MD
Mohammadtaymour@gmail.com+201006588699
Backup ContactWaleed M El-Khayat, MD
Waleed_elkhyat@yahoo.com01005135542

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026