Meditation, Mindfulness
Conditions
Keywords
mindfulness, functional brain network, neuroimaging, meditation
Brief summary
The purpose of this study is to investigate functional brain network in altered meditation state with multimodal neuroimaging.
Detailed description
1. Recruiting participants by approaching mindfulness training, poster, and websites. 2. Completing Questionnaires, Tests, and other materials for experiments. 3. Examining Functional Brain Network of Internal and External Meditation of practitioners with a meditation using multimodal neuroimaging. 4. Collecting and evaluating data about the connection of internal and external meditation with multimodal neuroimaging and identifying the function related to meditation state.
Interventions
DEVICEexternal meditation guided audio
Examining DMN connectivity and CSF flow in external meditation state by External Meditation Instruction Audio.
DEVICEinternal meditation guided audio
Examining DMN connectivity and CSF flow in external meditation state by Internal Meditation Instruction Audio.
Sponsors
Shanghai Mental Health Center
School of Biomedical Engineering, Shanghai Jiao Tong University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* A sufficient level of education to understand study procedure and be able to communicate with site personnel. * 18-60 years old. * Interested in meditation. * No metal or electronic implants in the body; no prosthesis (metal braces, dentures, etc.); no claustrophobia; no tattoos, piercings, etc.; no makeup on the day of the experiment. * Right-handed.
Exclusion criteria
* The participant has a contraindication to MRI examination, such as claustrophobia. * The participant is physically unfit for MRI, such as having a metal implant. * The participant has a history of neurological or psychiatric disorders, or is taking any chronic medications that may interfere with the experiment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Five Facet Mindfulness Questionnaire(FFMQ) | Week 1 | FFMQ is a validated, self-administered questionnaire that measures the tendency to act with mindfulness. Its 39 items are assessed on a Likert scale from 1 to 5 (i.e., "never or very rarely true" to "very often or always true"). The higher scores on the scale convey the higher tendency to act with mindfulness. |
| CSF pulsation index | Week 1 | CSF pulsation index, calculated by the number of CSF pulsation per minute. |
| Functional connectivity | Week 1 | Checking functional connectivity in major resting-state brain networks (such as DMN). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mindfulness positive awareness examined by Mindful Attention Awareness Scale (MAAS) | Week 1 | MAAS is a validated, fifteen-item self-report measure on which the items are scored using a six-point rating scale (1 = almost always and 6 = almost never). The global score of the scale is obtained by calculating the mean score of each participant's responses, and higher scores on the scale convey the higher levels of dispositional mindfulness. |
| The ability of self-compassion examined by Self-Compassion Scale(SCS) after 1-week practice of internal and external mindfulness | Week 1 | SCS is a validated, 26-item self-report measure on which the items are scored using a five-point Likert scale scored from 1 (almost never) to 5 (almost always). The higher total score on the scale indicates a higher level of self-compassion. |
| Cognitive Flexibility Inventory(CFI) | Week 1 | CFI is a validated, self-reported measure of cognitive flexibility，which consists of 20 statements scored from 1 ( "definitely disagree") to 7( "definitely agree."). The scores for all items are pooled to generate a total score of 20 to 140. Higher total scores indicate the increasing level of cognitive flexibility. |
| Perceived Stress Scale(PSS) | Week 1 | PSS is a validated, self-reported measure of psychological stress level. There are 10-items scored from 0 (never) to 4 (very often). The scores for all items are pooled to generate a total score in the range of 0 to 40. Higher total scores indicate the increasing level of psychological stress. |
| The Chinese version of Freiburg Mindfulness Inventory(FMI-13) | Week 1 | FMI-13 is a validated, thirteen-item self-report measure on which the items are scored using a four-point Likert scale ranging from 1 (strongly disagree) to 4 (strongly agree). This short form was used for measuring mindfulness traits, and higher scores on the scale convey the higher levels of mindfulness trait. |
Countries
China
Contacts
STUDY_CHAIRQing Fan
Shanghai Mental Health Center
STUDY_CHAIRJie Luo
School of Biomedical Engineering, Shanghai Jiao Tong University
Outcome results
None listed