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The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery

The Effect of Centella Asiatica Cream on Scar Tenderness in Patients Who Underwent Open Carpal Tunnel Release Surgery

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05017467
Enrollment
280
Registered
2021-08-23
Start date
2011-01-01
Completion date
2020-04-01
Last updated
2021-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To Prevent Scar Formation for Patients Underwent Surgery

Keywords

carpal tunnel syndrome, centella asiatica, surgery, cosmetic outcome, wound healing

Brief summary

The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.

Detailed description

Aim: This study was performed to evaluate the efficacy of centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release surgery.

Interventions

DRUGundefinedCentella Asiatica Extract

All patients were asked about scar hypertrophy, scar tenderness, and pillar pain. The scar assessment was performed using the Vancouver Scar Scale (VSS) at the one, three and 6 months after surgery. Patients were asked to complete pre- and postoperative functional evaluations. The VAS score and QuickDASH test was used

Sponsors

Konya Numune Hospital
CollaboratorOTHER_GOV
Mustafa Balevi,MD
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

280

Intervention model description

280 operated patient with carpal tunnel release surgery.

Eligibility

Sex/Gender
ALL
Age
19 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

patient underwent open carpal tunnel release surgery -

Exclusion criteria

before hand surgery and recurrent carpal tunnel release surgery. \-

Design outcomes

Primary

MeasureTime frameDescription
centella asiatica extrate10 yearstreatment

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026