Dysexecutive Syndrome
Conditions
Brief summary
Executive functions are defined as the mental functions necessary for an individual to adapt to a complex or new environment that requires freedom from automatic and routine behavior. Deficits in executive functions are described under the term dysexecutive syndrome, and call into question the quality of social and professional life as well as the autonomy of patients. The usual methods of identifying dysexecutive syndrome are based essentially on batteries of neuropsychological tests known as paper and pencil. However, these tests may lack sensitivity, in that they assess the patient in a very structured setting, very different from real life conditions, which are full of distractions and choices to be made. Evaluations on real tasks are more rarely used but have the advantage of observing the difficulties encountered by a patient in everyday life. Two tests of this type have been set up in the Neurology Department of the Hôpital d'Instruction des Armées Percy, and are integrated into the routine care of patients with a dysexecutive syndrome. For this purpose, a room in the department has been set up as a studio in order to reproduce as much as possible an everyday life environment, in which executive functions, fine motor skills, neurovegetative functions, emotional state, posture, locomotor skills and visual information capture can be measured ecologically.
Interventions
BEHAVIORALChocolate cake
The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).
BEHAVIORALLego model
The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).
DEVICEMeasurement of sensorimotor abilities
The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).
OTHERMeasurement of facial expression of emotions
Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).
Sponsors
Direction Centrale du Service de Santé des Armées
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients with a dysexecutive syndrome OR healthy subjects * Over 18 years-old
Exclusion criteria
* Patients * Psychiatric pathology (except for Post-Traumatic Stress Disorder) * Pregnant or breastfeeding woman * Healthy subjects * Neurologic or psychiatric pathology * Pregnant or breastfeeding woman
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lowest number of errors on the executive tasks over the 4 visits | Until the end of the study (3 years) | An error is defined as: an omission, an addition, a substitution, an estimation error, a question or a commentary The number of errors will be calculated for each task at each visit. The lowest number will be retained to compare the 2 groups. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lowest number of errors on the Lego model task over the 4 visits | Until the end of the study (3 years) | An error is defined as: an omission, an addition, a substitution, an estimation error, a question or a commentary The number of errors will be calculated for the Lego model task at each visit. The lowest number will be retained to compare the 2 groups. |
| Lowest number of errors on the chocolate cake task over the 4 visits | Until the end of the study (3 years) | An error is defined as: an omission, an addition, a substitution, an estimation error, a question or a commentary The number of errors will be calculated for the chocolate cake task at each visit. The lowest number will be retained to compare the 2 groups. |
Countries
France
Contacts
Primary ContactFlavie BOMPAIRE, MD
Outcome results
None listed