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Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance

Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05011318
Acronym
FRESH
Enrollment
162
Registered
2021-08-18
Start date
2021-08-25
Completion date
2023-06-15
Last updated
2023-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability, Skin Conductance

Brief summary

This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.

Detailed description

We hypothesize that increased cognitive fatigue would vary as a function of heart rate variability and skin conductance. A machine learning model will be developed that predicts cognitive fatigue through these physiological responses (Lee et al., 2021). Individual differences (i.e., age, gender, caffeine and food intake, body mass index, skin temperature, sleep quality, baseline physiology and behavioural performance) will be examined and accounted for.

Interventions

OTHERBaseline

5-min urban park video clip (Presented on a TV)

OTHERFatigue Manipulation

20-min 2-back task (Presented on a computer)

Sponsors

National Research Foundation, Singapore
CollaboratorOTHER_GOV
Ministry of National Development, Singapore
CollaboratorOTHER_GOV
Housing and Development Board, Singapore
CollaboratorOTHER_GOV
Nanyang Technological University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Singapore-based * Non-clinical * 18-35years

Exclusion criteria

* Individuals with hearing difficulties or failing to meet the minimal threshold for normal hearing * Individuals with a history of ear, developmental, neurological, or psychiatric disorder

Design outcomes

Primary

MeasureTime frameDescription
2-Back Task (Change)during fatigue manipulationChange in Accuracy over time
Fatigue State Questionnaireup to 5 mins after fatigue manipulationFatigue State Questionnaire Score
Electrocardiograph (Change)during fatigue manipulationChange in Heart Rate Variability over time
Electrodermal Activity (Change)during fatigue manipulationChange in Skin Conductance Level over time

Countries

Singapore

Contacts

Primary ContactKar Fye Alvin Lee, PhD
alvin.lee@ntu.edu.sg+6591557981
Backup ContactGEORGIOS CHRISTOPOULOS, PhD
georchris7@gmail.com+6594898379

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026