Obesity
Conditions
Keywords
nutrition, Diet, Ketogenic, Diet, Carbohydrate-Restricted
Brief summary
The goal of this trial is to pilot test our existing very low carbohydrate diet intervention, adapted for young adults.
Detailed description
Obesity increases the risk of a variety of illnesses such as heart disease, type 2 diabetes, cancer, sleep apnea, asthma, and depression. While advice from the Centers for Disease Control, American Heart Association, and the National Institutes of Health recommend a low-fat diet with a focus on whole grains and lean meats, research shows that a very low-carbohydrate diet may be more effective at reducing body mass index (BMI). Given the disconnect between recommendations and research, higher quality, long term, large trials are needed. In preparation for that research, the investigators plan to pilot test a very low-carbohydrate diet program, the OWL study (Online Wellness and Lifestyle Study), for 30 young adults followed over 4 months.
Interventions
BEHAVIORALdiet and lifestyle program
See description of main arm.
Sponsors
Nutrition Science Initiative
University of Michigan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-25 * Obese (BMI ≥ 30) * Sufficient control over diet * Access to internet and texting * Living in the United States * Willing and able to follow intervention and complete measurements
Exclusion criteria
* Non-English speaking * Pregnant, breastfeeding, or planning to be in the next 6 months * Vegan or vegetarian * Currently enrolled in weight loss program * Taking medications known to cause weight loss or gain * Taking glucose-lowering medications other than metformin * Type 1 diabetes * Cancer * Heart failure * Kidney failure * History of eating disorders * Untreated psychiatric disorder * History of or planned weight loss surgery * Consumption of greater than 30 alcoholic beverages per week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in percent bodyweight | 4 months | Measured with bodyweight scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in HbA1c | 4 months | Measured with at-home finger prick analyzed in CLIA certified lab |
Countries
United States
Outcome results
None listed