Cancer-related Fatigue, Light; Therapy, Complications
Conditions
Keywords
Cancer-related fatigue, White light therapy, Chemotherapy, Clinical trial
Brief summary
White light therapy is one of the non-pharmacological methods in the management of fatigue. Cancer-related fatigue (CRF) is a persistent, subjective sense of physical, emotional, and/or cognitive tiredness or burnout. It is associated with cancer or cancer treatment from the first diagnosis until the end of life that is not proportional to recent physical activity. It was founded that 10,000 Lux bright white light administered in the morning hours reduced fatigue by 17% in patients with cancer and that the mean fatigue scores of patients decreased from 30.37 to 9.48 compared to before the light administration. According to NCCN (2020), white light of 10,000 Lux can be applied for 30-90 minutes in the morning hours to regulate sleep and manage fatigue in the post treatment period as well as in cancer patients receiving active treatment. However, studies on this subject consist of small sample groups, and more studies are needed to identify the risks and benefits of the application and to determine the optimal application time and duration. The present study was aimed to evaluate the effect of white light on the fatigue levels of patients with gynecological cancer who were treated with chemotherapy. The patients with high levels of fatigue in every dimension were selected so as to have a homogeneous group. The research hypotheses were determined as follows: H0: White light has no effect on fatigue levels in patients with gynecological cancer. H1: White light reduces fatigue levels in patients with gynecological cancer.
Interventions
OTHERWhite Light Application
White Light Therapy
Sponsors
Eskisehir Osmangazi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* had a normal state of consciousness, * had no communication disorders, did not work in the night shift, * had a general fatigue level score of ≥1 according to the Brief Fatigue Inventory
Exclusion criteria
* had natural/artificial lenses, * used medication that causes photosensitivity (tetracycline, doxycycline, nalidixic acid, voriconazole, amiodarone, hydrochlorothiazide, naproxen, piroxicam, chlorpromazine) * had a change in their treatment plan in the last 6 weeks were not included in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| White light changes general fatigue scores | general fatigue levels of patients on 0., 9. and 21. days | White light changes general fatigue levels in patients with gynecological cancer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| White light changes activity fatigue scores | activity fatigue levels of patients on 0., 9. and 21. days | White light changes activity fatigue levels in patients with gynecological cancer |
Countries
Turkey (Türkiye)
Outcome results
None listed