Articular Disease
Conditions
Keywords
Osteoarticular infection, Bacteria, Urinary tract infections
Brief summary
Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are : * To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome * To compare OAI of urinary origin with those with another origin
Detailed description
This retrospective study will be conducted on medical files. Patients will be mainly selected on : * A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020. * Adult patients 18 year's old or older * Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features) The followed OAI are not included : * Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis * Brucellosis ; Lyme disease Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators. OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy. * Characteristics of three populations will be compared : * \- OAI of urinary origin * \- OAI of another origin (skin, etc) * \- OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.
Interventions
OTHERGroups/Cohortes
Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020
Sponsors
Hôpital NOVO
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Subject aged 18 years and over at the time of diagnosis * Osteoarticular infection (septic arthritis, spondylodiscitis), by a bacterium or a fungus, proven by a bacteriological sample in situ or in the blood by positive blood culture (with an unequivocal clinical, biological and imaging feature), * Diagnosed between 01/01/2010 and 12/31/2020 (11 years) * Hospitalization in the rheumatology department of CH René Dubos, Pontoise
Exclusion criteria
* Bacterial infection due to the following germs: mycobacteria, brucella, Borrelia * Early infection on joint prosthesis * Peripheral osteomyelitis * Osteoarticular infection without bacteriological proof
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identification of the spectrum of osteoarticular infections in adult, in a rheumatology department | Through study completion, an average of 1 year | The purpose of this database is to describe the spectrum of osteoarticular infections in adults, non-tuberculosis germs, in a rheumatology department of a CHG during the 2010s |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of urinary origin in osteoarticular infections in adults, compared with other origins | Through study completion, an average of 1 year | The second purpose of this database is to identify the characteristics of osteo-articular infections of urinary origin |
Countries
France
Outcome results
None listed