Children, Probiotics, Skin Care
Conditions
Brief summary
Probiotics, a component that is generally referred to as a living microorganism or a microorganism present in a host. Most studies have shown that probiotics can regulate immune function in the body. Many studies have attempted to understand whether the use of probiotics can prevent allergic diseases or not.
Interventions
DIETARY_SUPPLEMENTPlacebo
A pack of powder without probiotics. 1 pack / day
DIETARY_SUPPLEMENTProbiotics Lactobacillus salivarius AP-32
A pack of powder with probiotics Lactobacillus salivarius AP-32 1 pack / day
DIETARY_SUPPLEMENTProbiotics Bifidobacterium animalis subsp. lactis CP-9
A pack of powder with probiotics Bifidobacterium animalis subsp. lactis CP-9 1 pack / day
DIETARY_SUPPLEMENTProbiotics Lactobacillus rhamnosus LGG
A pack of powder with probiotics Lactobacillus rhamnosus LGG 1 pack / day
Sponsors
Glac Biotech Co., Ltd
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Masking description
Double-blind.
Intervention model description
Skin Care in children.
Eligibility
Sex/Gender
ALL
Age
1 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* Estimated by PI.
Exclusion criteria
* Be allergic to medicine * Take medicine like immune inhibition, or steroid injection in two weeks * Participate in another clinical research or immune therapy in one month * Have severe disease * Inappropriate for this trial judged by PI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Skin severity scoring | 3 months | According to the scale to estimate skin severity |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood analysis | 3 months | ELISA analysis |
| NGS in gastrointestinal tract | 3 months | The difference of NGS ( Next Generation Sequence ) in gastrointestinal tract between 0 month and the 3rd month. |
| Life quality | 3 months | The questionnaire of life quality in three months. |
Countries
Taiwan
Contacts
Primary ContactKuo Ho-Chang
Outcome results
None listed