Health, Subjective
Conditions
Brief summary
This study will be evaluated safety of undenatured collagen type II (UCII) supplement in 60 healthy volunteer. Liver function test, renal function test, and adverse event will be assessed.
Detailed description
This study will be evaluated safety of undenatured collagen type II (UCII) supplement in 60 healthy volunteer. The undenatured collagen type II (UCII) supplement 40 mg will be taken once daily for 2 months. Liver function test, renal function test, and adverse event will be assessed before and after taking for 1 and 2 months.
Interventions
DIETARY_SUPPLEMENTundenatured collagen type II (UCII) supplement
The undenatured collagen type II (UCII) supplement 40 mg will be taken once daily for 2 months.
Sponsors
Chulalongkorn University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 20-60 years * No taking collagen supplement more than 2 weeks * No collagen and protein allergy * No liver and renal disease * Have a willingness to participate in the study
Exclusion criteria
* Uncontrolled disease * Have complication symptom during study * Pregnancy or lactation * Cannot follow the protocol * During participated in other studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Aspartate aminotransferase value | 2 months | Aspartate aminotransferase value (U/L) in blood sample |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Alkaline phosphatase value | 2 months | Alkaline phosphatase value (U/L) in blood sample |
| Alanine transaminase value | 2 months | Alanine transaminase value(U/L) in blood sample |
| Blood urea nitrogen value | 2 months | Blood urea nitrogen value (mg/dl) in blood sample |
| Creatinine value | 2 months | Creatinine value (mg/dl) in blood sample |
| Adverse event | 2 months | using questionnaire (Yes or No) |
Outcome results
None listed