Missed Abortion
Conditions
Brief summary
Efficacy of sublingual versus vaginal misoprostol in termination of first trimester missed abortion
Detailed description
study will be made on female patients with first trimester missed abortion confirmed by ultrasound . Participants will be divided into 2 groups one group (A) will receive sublingual Misoprostol and the other group(B) will receive vaginal Misoprostol as a 800 micro grams every 4 hours in both groups up to five doses the aim of the study is to compare efficay of sublingual and vaginal Misoprostol in complete termination of first trimester missed abortion and which route is the best will less side effects.
Interventions
DRUGMisoprostol Pill
sublingual versus vaginal Misoprostol in termination of first trimester missed abortion
Sponsors
Cairo University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Women with an ultrasound diagnosis of missed abortion \< 13 weeks gestation without any clinical criteria of Inevitable abortion.
Exclusion criteria
* Patients refused the medical treatment. * Patients have contraindications of the drug (Misoprostol). * Missed abortion associated with any signs of sepsis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The occurance of complete abortion within 24 hours with Misoprostol drug | Within 24 hours | Efficacy of sublingual and vaginal Misoprostol in complete termination of first trimester missed abortion |
| Which route is the best and less side effects in complete termination of first trimester missed abortion by Misoprostol drug | within 24 hours | Vaginal versus sublingual route of administration of Misoprostol for complete termination of first trimester missed abortion |
Contacts
Primary ContactAhmed Emam
Outcome results
None listed