White Spot Lesion
Conditions
Brief summary
This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.
Interventions
OTHERTime of assessment
Immediate and after one month and after two months
Sponsors
Benha University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Intervention model description
Split mouth technique
Eligibility
Sex/Gender
ALL
Age
15 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment. * These patients will be selected according to age groups between 15-25 years old * good oral hygiene * free of destroying habits for dental tissues
Exclusion criteria
* Bruxism * soft drinks consumption * acid regurgitation, etc.). * Selected teeth having any cracks, malformations, dysplasia or caries.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in remineralization from base line to time limit | Immediate and one month and two months | Change in its density in digital xray |
| changes of appearance from base line photograph to time limit | Immediate and one month and two months | White spots disappear on digital photography |
Countries
Egypt
Outcome results
None listed