Capillary Malformation-Arteriovenous Malformation, Port-Wine Stain, Sturge-Weber Syndrome, Vascular Diseases, Vascular Malformation, Vascular Tumor
Conditions
Keywords
Vascular Diseases, Laser treatment, Capillary Malformation, Port-Wine Stain, Vascular Tumor
Brief summary
Laser treatment (LT) is the first-line treatment for Vascular Pathology. However even when LT is based on the selective photothermolysis it causes the first-degree burns. While being typically benign by affecting only the epidermis, or outer layer of skin, the burn site is remaining red, dry, and very painful. As Haemoblock contains nanoparticles of silver and is known for both bactericidal and bacteriostatic effects, it likely decreases the potential for infection postoperatively. Furthermore, after fibrin replaces the superficial structure Hemoblock-albumin, the polyacrylate matrix is plasmolyzed which initiates the cascade of signals required for the tissue regeneration processes. Objective of the study was to examine the effect of the Regenerative Solution Hemoblock in lowering postoperative complications in children diagnosed with Vascular Pathology undergoing a laser surgery if delivered with transdermal patches.
Interventions
Delivering with transdermal patches
Delivering with transdermal patches
Sponsors
Study design
Masking description
Participants, clinicians and the research team, completing baseline and follow-up assessments were masked to group allocation.
Eligibility
Inclusion criteria
* clinically diagnosed Vascular Pathology
Exclusion criteria
* age * severe allergic reaction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preventing negative outcomes of postoperative infection | Early postoperative period and at 3 weeks | Validated scales |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Preventing prolonged functional recovery | Early postoperative period and at 3 weeks | Validated scales |
Other
| Measure | Time frame | Description |
|---|---|---|
| Preventing likelihood of mental health issues | Early postoperative period and at 3 weeks | Validated scales |
Countries
Russia