Acute Coronary Syndrome, Acute Coronary Syndrome With Renal Dysfunction
Conditions
Brief summary
The project is planed to explore the impact of LTBP4 and other matrix protein and potentially related biomarkers on renal outcomes, cardiac outcomes and all-cause mortality in patients with suspected acute coronary syndrome (ACS).
Detailed description
The investigators will collect the blood samples from patients with suspect ACS. LTBP4 will be the first matrix protein that are going to understand. Upon hospital arrival, blood samples around 8 ml will be collected and the 2nd collection will be two weeks to one month after the event. The third collection will be one year later. In the between, if any ACS event develop, blood samples will be collected as protocols.
Interventions
None listed
Sponsors
National Taiwan University Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
\- acute coronary syndrome patients
Exclusion criteria
\- cardiogenic shock, pregnancy, end-stage renal disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of renal functions | One month, Six month and one year | The investigators will follow up Cr and eGFR levels correlate with LTBP4 levels |
| All cause mortality | 3 years | — |
| Incidence of hospitalization | 3 years | — |
| Incidence of required myocardial revascularization | 3 years | — |
Countries
Taiwan
Contacts
Primary ContactChi-Ting Su, MD. MPH, PhD
Backup ContactYue-Jhu Huang, MS
Outcome results
None listed