Infections With Enterobacteria Producing Carbapenemases at the University Hospitals of Strasbourg

Infections With Enterobacteria Producing Carbapenemases at the University Hospitals of Strasbourg - Descriptive Epidemiology and Risk Factors for Infection in the Event of Colonization

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04995965

Acronym

CARBA

Enrollment

274

Registered

2021-08-09

Start date

2021-08-06

Completion date

2022-01-06

Last updated

2021-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nfections, Enterobacterial

Keywords

nfections, Enterobacterial, carbapenemases, producers of a carbapenemase

Brief summary

Infections with enterobacteria producing carbapenemases at the University Hospitals of Strasbourg - descriptive epidemiology and risk factors for infection in the event of colonization There is a worrying situation of an increase in the number of patients colonized with carbapenemase-producing Enterobacteriaceae (CPE) at HUS. 7 to 15% of patients colonized with EPC would develop an infection with EPC. The cohorts published mainly concern patients hospitalized in intensive care. The associated mortality reported in the literature is high (\> 25%) and greater than that associated with infection with the same bacterium sensitive to carbapenems.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Major subject (≥18 years old) * Subject hospitalized at HUS between 01/01/2011 and 07/31/2021 * Clinical sample or rectal screening smear finding an enterobacterium producing a carbapenemase (EPC) * Subject not having expressed their opposition to participating in the study

Exclusion criteria

* Subject having expressed opposition to participating in the study * Subject under guardianship or guardianship * Subject under safeguard of justice

Design outcomes

Primary

Measure	Time frame
Retrospective study of Enterobacteriaceae infections producing carbapenemases	Files analysed retrospectively from January 01, 2011 to July 31, 2021 will be examined]

Countries

France

Contacts

Primary ContactYves HANSMANN, MD, PhD

yves.hansmann@chru-strasbourg.fr33 3 69 55 09 78

Backup ContactSaïd CHAYER, PhD, HDR

said.chayer@chru-strasbourg.fr33 3 88 11 66 90

Outcome results