Metabolism and Nutrition Disorder
Conditions
Brief summary
The validity (by alcohol burning and gas infusions) and reliability (day-to-day variability in healthy subjects) of six metabolic carts will be compared.
Interventions
DEVICEAssessment of resting energy expenditure
We will assess the resting metabolic rate and respiratory exchange ratio of twenty healthy adults, with every metabolic cart on two days in the morning. The assessment will last 30 minutes on each metabolic cart, with 15-minute breaks between measurements. The order of the metabolic carts will be randomly selected and replicated the second day.
Sponsors
Pennington Biomedical Research Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy male or female. * Age 18-65 y. * BMI between 18.5 kg/m2 and 40 kg/m2 (inclusive). * Are willing to fast and not consume non-caloric stimulant for 10h before the assessments, and during the stay in the center. * Are willing to avoid moderate or vigorous physical activity during 24h before the visits.
Exclusion criteria
* Smoking or use of tobacco products within the last 3 months * Diagnosed with diabetes. * Previous bariatric surgery (or other surgeries) for obesity or weight loss. * Use of medications affecting metabolism or sleep. * History of neurological disease. * History of cardiovascular disease, including hypertension, or other chronic diseases. * Pregnant, planning to become pregnant, or breastfeeding * Claustrophobia impeding to stay calm under a plastic canopy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Resting metabolic rate | 30 minutes | Indirect calorimetry |
Countries
United States
Outcome results
None listed