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Ultrasound Guided Bilateral Superficial Cervical Plexus Block in Patients Undergoing Total Thyroidectomy.

Ultrasound Guided Bilateral Superficial Cervical Plexus Block Versus Local Wound Infiltration in Patients Undergoing Total Thyroidectomy: A Randomized Controlled Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04993521
Acronym
BSCPB_Block
Enrollment
60
Registered
2021-08-06
Start date
2019-02-01
Completion date
2021-05-15
Last updated
2021-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia Obtained With a Local Wound Infiltration of Lidocain, Analgesia Obtained With a Ultrasound Guided Cervical Plexus Block Using Lidocain, Postoperative Pain

Brief summary

The present study compared the efficacy of bilateral superficial cervical plexus block (BSCPB) versus local wound infiltration (LWI) regarding the postoperative opioid consumption in patients undergoing total thyroidectomy

Detailed description

We performed a double-blind, randomised, controlled trial that recruited patients undergoing total thyroidectomy at the Suez Canal University Hospital during the period between February 2019 and January 2021. Patients were eligible if they were older than 20 years, had an American Association of Anesthesiologists' (ASA) level of I-II, and were scheduled for total thyroidectomy. We excluded patients with documented allergies to the study's intervention materials, moderate-to-severe obesity, \> 1st-degree heart block, chronic pulmonary or cardiac diseases, hepatic or renal dysfunction, and/or coagulopathies. All patients were required to fill out informed consent before enrollment. Eligible patients were randomly allocated in a 1:1 ratio to receive BSCPB or LWI using the computer software program (www. Randmizer.org) and allocation sequences were done using opaque, closed envelopes. The BSCPB group received BSCBP (after general anaesthesia but before the start of surgery) from two syringes containing ropivacaine 0.5 % and LWI with saline. The LWI group received LWI with ropivacaine 0.5% and the BSCPB from two syringes containing saline. The primary outcome of the present study was postoperative opioid consumption in the first postoperative day. The secondary outcomes included the total intraoperative fentanyl and isoflurane consumption, time to first required analgesic, and VAS during the first 24 hours postoperatively.

Interventions

PROCEDUREBlock type

Regular block type

Sponsors

Ahmed Mohamed Abdelrahman
CollaboratorUNKNOWN
Mahmoud Ahmed Mewafy
CollaboratorUNKNOWN
Abdelrhman Alshawadfy
CollaboratorUNKNOWN
Haidi Abd-Elzaher
CollaboratorUNKNOWN
Hamada Fathy
CollaboratorUNKNOWN
Mohamed Faisal
CollaboratorUNKNOWN
University Hospital, Linkoeping
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

A Randomized Controlled Study

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

ASA I-II, and were scheduled for total thyroidectomy \-

Exclusion criteria

documented allergy to study's intervention, moderate-to-severe obesity, \> 1st-degree heart block, chronic pulmonary or cardiac diseases, hepatic or renal dysfunction, and/or coagulopathies. All patients were required to fill the informed consent before enrollment.

Design outcomes

Primary

MeasureTime frameDescription
postoperative opioid consumption in the first postoperative day24 hourspostoperative opioid consumption in the first postoperative day in milligrams

Secondary

MeasureTime frameDescription
total intraoperative fentanyl (mg) and isoflurane consumption (ml)6 hourstotal intraoperative fentanyl and isoflurane consumption in micrograms and ml
time to first required analgesic6 hourstime to first required analgesic
VAS (10 cm; range): Pain average (VAS) for the first 24 hours postoperativelyevery 6 hours until 24 hours postoperativelyVAS (10 cm; range) Pain average (VAS) for the first 24 hours postoperatively

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026