Analgesia Obtained With a Local Wound Infiltration of Lidocain, Analgesia Obtained With a Ultrasound Guided Cervical Plexus Block Using Lidocain, Postoperative Pain
Conditions
Brief summary
The present study compared the efficacy of bilateral superficial cervical plexus block (BSCPB) versus local wound infiltration (LWI) regarding the postoperative opioid consumption in patients undergoing total thyroidectomy
Detailed description
We performed a double-blind, randomised, controlled trial that recruited patients undergoing total thyroidectomy at the Suez Canal University Hospital during the period between February 2019 and January 2021. Patients were eligible if they were older than 20 years, had an American Association of Anesthesiologists' (ASA) level of I-II, and were scheduled for total thyroidectomy. We excluded patients with documented allergies to the study's intervention materials, moderate-to-severe obesity, \> 1st-degree heart block, chronic pulmonary or cardiac diseases, hepatic or renal dysfunction, and/or coagulopathies. All patients were required to fill out informed consent before enrollment. Eligible patients were randomly allocated in a 1:1 ratio to receive BSCPB or LWI using the computer software program (www. Randmizer.org) and allocation sequences were done using opaque, closed envelopes. The BSCPB group received BSCBP (after general anaesthesia but before the start of surgery) from two syringes containing ropivacaine 0.5 % and LWI with saline. The LWI group received LWI with ropivacaine 0.5% and the BSCPB from two syringes containing saline. The primary outcome of the present study was postoperative opioid consumption in the first postoperative day. The secondary outcomes included the total intraoperative fentanyl and isoflurane consumption, time to first required analgesic, and VAS during the first 24 hours postoperatively.
Interventions
Regular block type
Sponsors
Study design
Intervention model description
A Randomized Controlled Study
Eligibility
Inclusion criteria
ASA I-II, and were scheduled for total thyroidectomy \-
Exclusion criteria
documented allergy to study's intervention, moderate-to-severe obesity, \> 1st-degree heart block, chronic pulmonary or cardiac diseases, hepatic or renal dysfunction, and/or coagulopathies. All patients were required to fill the informed consent before enrollment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative opioid consumption in the first postoperative day | 24 hours | postoperative opioid consumption in the first postoperative day in milligrams |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| total intraoperative fentanyl (mg) and isoflurane consumption (ml) | 6 hours | total intraoperative fentanyl and isoflurane consumption in micrograms and ml |
| time to first required analgesic | 6 hours | time to first required analgesic |
| VAS (10 cm; range): Pain average (VAS) for the first 24 hours postoperatively | every 6 hours until 24 hours postoperatively | VAS (10 cm; range) Pain average (VAS) for the first 24 hours postoperatively |
Countries
Sweden