Magnetic Resonance Imaging
Conditions
Brief summary
T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution. In this study we aim to characterise the normal appearance of T1rho in the brain parenchyma in healthy participants. T1rho values will be measured in normal brain structures.
Interventions
DIAGNOSTIC_TESTT1rho imaging
Magnetic Resonance Imaging using T1rho
Sponsors
Chinese University of Hong Kong
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
\- Male and female volunteers greater than or equal to 18 years of age
Exclusion criteria
* Subjects with a contraindication to magnetic resonance imaging such as the presence of metallic implants, claustrophobia and pregnancy. * Subjects with previous severe allergic or anaphylactoid reaction to a gadolinium contrast agent, or contraindication to contrast gadolinium administration, such severe renal disease or acutely deteriorating renal function, who would be at risk of nephrogenic systemic fibrosis * Subjects who are unable to tolerate the scan without moving the head as a result of symptoms such as tremor, spasticity, involuntary movements and spasms, cognitive impairment, coughing, and shortness of breath.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| T1rho value in normal grey and white matter in healthy volunteers | Up to 2 months | T1rho value (measured on T1rho weighted MRI) in normal grey and white matter in healthy volunteers |
Countries
Hong Kong
Contacts
CONTACTTiffany So
Outcome results
None listed