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Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients

Ultrasonic Perfusion Imaging for Monitoring Mastectomy Skin Microcirculation in Post-mastectomy Irradiated Patients Before and After Autologous Fat Transfer

Status
Enrolling by invitation
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04992650
Enrollment
15
Registered
2021-08-05
Start date
2021-03-01
Completion date
2026-11-15
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Reconstruction, Fat Grafting, Radiation Dermatitis, Radiation Fibrosis

Brief summary

The purpose of this study is to evaluate post-mastectomy breast skin blood supply (perfusion) after radiation therapy, and before and after fat grafting to the breast(s).

Interventions

PROCEDUREFat grafting

Fat grafting

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Breast cancer patients undergoing immediate tissue expander or implant reconstruction requiring radiation therapy * Have undergone mastectomy

Exclusion criteria

* Patients who are unwilling to participate

Design outcomes

Primary

MeasureTime frameDescription
Radiation Fibrosis12 monthsNumber of subject to experience radiation fibrosis

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORChristin A. Harless, M.D.

Mayo Clinic

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 2, 2026