Femoroacetabular Impingement
Conditions
Brief summary
Femoral acetabular impingement (FAI) is a common disease of the hip joint. In this study, whole-genome sequencing was used to further explore the pathogenesis of this disease.
Detailed description
Femoral acetabular impingement (FAI) is a group of chronic hip pain caused by the impact between the proximal femur and the edge of the acetabulum due to the anatomical abnormality of the hip joint, which damages the labrum and adjacent cartilage, and causes limited hip movement, especially limited flexion and internal rotation. However, the specific etiology of FAI is still unknown at present. The application of genome-wide, exon and transcription research methods to the study of hip impaction syndrome can uncover key differentially expressed genes and provide a theoretical basis for the study of FAI.
Interventions
OTHERExposures
Exposures
Sponsors
Peking University Third Hospital
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
15 Years to 70 Years
Inclusion criteria
* The patient underwent preoperative imaging and was diagnosed with FAI. The patient complained of pain in the hip, hip, or thigh, and had a positive hip flexion impact test.
Exclusion criteria
* Patients with hip surgery history, hip osteoarthritis, necrosis of the femoral head, hip infection, hip dysplasia and other hip diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The patients were clinically diagnosed with FAI (femoral acetabular impingement) and underwent arthroscopic surgery, then clinical samples were collected. | The patient was diagnosed with FAI, and conservative treatment was ineffective for an average of 6 months. | Peripheral blood from 100 patients with femoral acetabular impingement syndrome was collected and DNA was extracted. |
Countries
China
Outcome results
None listed