Respiratory Failure, Tracheostomy Complication
Conditions
Keywords
Tracheostomy, Ventilation weaning, spontaneous breathing trial
Brief summary
This retrospective study aims to study characteristics of patients tracheotomized in the Lausanne ICU, both overall and by primary reasons of intubation. Ventilation data both before and after tracheotomy, weaning technique and timing are studied in this retrospective study.
Interventions
None listed
Sponsors
Piquilloud Imboden Lise
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients hospitalized in the Lausanne ICU between May 1st 2017 and November 31st 2018 with a tracheotomy and mechanically ventilated more than 72 hours.
Exclusion criteria
* Presence of a know opposition to participation to research projects * Patient tracheostomized specifically for ENT (ear-nose-throat) reason * Burn victim * Patient tracheostomized before his/her admission to the Lausanne ICU
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time from intubation to tracheotomy | Once, between time of intubation to time of tracheotomy, up to 60 days | Calculated from clinical information system (time of intubation, time of tracheotomy), calculated in hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comorbidities | At ICU admission | Collected at ICU admission |
| SOFA score (admission) | At ICU admission | Calculated at admission |
| Clinical Frailty Score | At ICU admission | Calculated at ICU admission |
| Age | At ICU admission | Collected from electronic patient files. |
| Weight | At ICU admission | Collected from electronic patient files. |
| Height | At ICU admission | Collected from electronic patient files. |
| Body mass index | At ICU admission | Calculated from weight and height |
| Predicted body weight (PBW) | At ICU admission | Calculated as such : Adult male: 50 + 0.91 (Height cm -152.4) / Adult female: 45 + 0.91 (Height cm -152.4) |
| Ventilation modalities and settings from intubation to tracheotomy | Once every day at 8am, between day after intubation to day before tracheotomy, up to 60 days | Ventilation modalities and settings recolted from electronic patient files. |
| Sedation opioid use from intubation to tracheotomy | Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days | Sedation use collected from electronic patient files. |
| Opioid use from intubation to tracheotomy | Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days | Opioid use collected from electronic patient files. |
| Neuromuscular blocking agent use from intubation to tracheotomy | Once every day at 8am and at time of minimal and maximal value, between day of intubation to day of tracheotomy, up to 60 days | Neuromuscular blocking agent use collected from electronic patient files. |
| Tracheotomy time | At time of tracheotomy, once, up to 60 days after intubation day | Collected from electronic patient files (day and hour) |
| Charlson comorbidity index | At ICU admission | Calculated at ICU admission |
| Ventilation settings and modalities from day of tracheotomy | 2 hours before tracheotomy | Collected from electronic patient files. |
| SOFA score (tracheotomy day) | Once, on the day of tracheotomy (worst value of the day of tracheotomy), up to 60 days after intubation day | Calculated from electronic patient files. |
| Ventilation modalities and settings from tracheotomy to mechanical ventilation weaning | Once per day, from day of tracheotomy to mechanical ventilation weaning, up to 60 days | Ventilation modalities and settings collected from electronic patient files. |
| Tracheotomy weaning strategies from tracheotomy to mechanical ventilation weaning | Once every day at 8am and at time of minimal and maximal value, from day of tracheotomy to day of mechanical ventilation weaning, up to 31 days | Data collected from electronic patient files. |
| Physical therapy sessions from tracheotomy to mechanical ventilation weaning | Once every day at 8am and at time of minimal and maximal value, from day of tracheotomy to day of mechanical ventilation weaning, up to 31 days | Data collected from electronic patient files. |
| Mechanical ventilation weaning day | Once (day 3 in a row of less than 12 hours of mechanical ventilation), up to 31 days after tracheotomy day | Data collected from electronic patient files. |
| SOFA score (mechanical ventilation weaning day) | Once (3rd consecutive day with less than 12-h of mechanical ventilation), up to 31 days after tracheotomy day | Calcutated from electronic patient files. |
| Ventilation modalities and settings from mechanical ventilation weaning day to decannulation or ICU discharge or death | Once every day at 8am and at time of minimal and maximal value, from day of mechanical ventilation weaning to decannulation or ICU discharge or death, up to 31 days | Collected from electronic patient files. |
| Physical therapy sessions from mechanical ventilation weaning day to decannulation or ICU discharge or death | Once every day at 8am and at time of minimal and maximal value, from day of mechanical ventilation weaning to decannulation or ICU discharge or death, up to 31 days | Collected from electronic patient files. |
| Hospital stay duration | Once, between day of hospital admission to day of hospital discharge, up to 2 years | Collected from electronic patient files and discharge letters |
| Outcome and specific treatments in ICU | Once, between day of hospital admission to day of hospital discharge, up to 2 years | Data recolted from electronic patient files |
| Correlation of ventilation settings and modalities and tracheotomy weaning strategies | Once, between day of hospital admission to day of hospital discharge, up to 2 years | Collected from electronic patient files and discharge letters |
| Tracheotomy type (percutaneous, surgical) | At time of tracheotomy, once, up to 60 days after intubation day | Collected from electronic patient files. |
Countries
Switzerland
Outcome results
None listed