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Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Comparison Between the Analgesic Effects of Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04986878
Enrollment
60
Registered
2021-08-03
Start date
2017-03-15
Completion date
2018-06-30
Last updated
2021-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatism Knee

Brief summary

Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).

Detailed description

Various approaches to the performance of peripheral nerve blocks for postoperative pain control in patients undergoing TKA have been described in the literature. These approaches include lumbar plexus block, femoral nerve block (FNB), with or without a sciatic nerve block, and most recently the ACB. FNB is a commonly used modality for postoperative analgesia after TKA. It is considered by some as the gold standard or the cornerstone of postoperative analgesia after TKA. However, FNB reduces quadriceps muscle strength essential for mobilization and active contribution in any physical rehabilitation program. Quadriceps weakness places the patients at risk of falling. which may be detrimental to postoperative recovery. The ACB has recently emerged as an appealing alternative to FNB as it is predominately a sensory nerve block of a more distal branch of the femoral nerve ( the saphenous nerve).

Interventions

An ultrasound machine (Philips; Model: OTD020, AcBel Polytech Inc., Taiwan) with a 5-10 MHz linear probe was used to perform the adductor canal block immediately postoperatively.

Sponsors

Aswan University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Masking description

A computer-generated randomization table will be used for patient allocation to one of the two study groups, The SACB group, and the CACB group. Randomization was done in blocks of 10 patients each. Patients' assignments were written in a sealed envelope that was only open after the patient consents to the study.

Intervention model description

The target population of this study will be patients undergoing primary total knee arthroplasty at Aswan l and Assiut university hospitals

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Patients scheduled for primary total knee arthroplasty with * American Society of Anesthesiologists (ASA) physical status I -III, * mentally competent and able to give consent for enrollment in the study.

Exclusion criteria

1. Patient younger than 18 years old or older than 70 years old 2. Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol. 3. Revision surgeries were excluded. 4. Impaired kidney functions and patients with coagulopathy were also excluded. 5. Chronic pain syndromes and patients with chronic opioid use defined as the use of regular daily doses of systemic narcotics for the past 6 months prior to the surgery. 6. BMI of 40 or more 7. Pregnancy (positive urine pregnancy test result in Preop area on the morning of surgery)

Design outcomes

Primary

MeasureTime frameDescription
postoperative pain scores by visual analogue score48 hoursvisual analogue score is a straight, vertical 10-cm line with the bottom point representing no pain = (0cm) and the top point representing the worst pain you could ever have = (10 cm).

Secondary

MeasureTime frameDescription
time to up and go test (minutes)48 hoursdetermines how long it takes a person to get out of a chair
six-minute walking test48 hourscalculates the distance that can be walked in 6 minutes
the 30-Second Chair test48 hoursdetermines how many times a person can rise from a chair and sit down again in 30 seconds while keeping their arms crossed over their chest

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026