Hypoxemia, Single Lung Ventilation
Conditions
Brief summary
Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries
Detailed description
Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube of choice in lung surgeries versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube intermittent two lung ventilation
Interventions
PROCEDURESingle lung ventilation by double lumen endotracheal tube
Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field
PROCEDURETwo lung ventilation by conventional single lumen endotracheal tube
Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Masking description
The patients will not know whether they are in the first or second group
Intervention model description
Two equal groups: the first group undergoing lung surgeries with single lung ventilation by double lumen endotracheal tube, the second group undergoing lung surgeries with two lung ventilation using conventional single lumen endotracheal tube
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age group: Adult patients from age of 21 years to 60 years * Sex: Both sexes * ASA Classification: patients with ASA classification II, III. * Elective lung surgeries using video assisted thoracoscopic surgeries.
Exclusion criteria
* Patients refuse to give informed consent. * ASA Classification: ASA IV. * Failure of thoracoscopic surgeries and continue as open thoracotomy * Patients with ischemic heart diseases, where hypoxemia might be preexisting, or patient be more vulnerable to hypoxemia whatever the technique or time of hypoxia. * Emergency lung surgeries. * Patients underwent previous lung surgeries of any cause. * Patients with pathology to the non-operated side.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of hypoxemia | Intraoperative to first 24 hours post operative | Hypoxemia in single and two lung ventilation by serial arterial blood gases |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of failure to correct Hypoxemia in single lung ventilation | Intraoperative | Stop lung isolation and procedure using two lung ventilation to correct hypoxia |
| Incidence of failure of two lung ventilation to create optimum surgical field | Intraoperative | Frequent stopping of ventilation and the surgent can't access the surgical field easily |
| Incidence of post operative complications | First 24 hours post operative | Any associated complications |
Countries
Egypt
Contacts
Primary ContactEsraa Abdellatif
Outcome results
None listed