Alzheimer Disease, Dementia; Alzheimer's Type (Etiology), Fall Risk, Elderly, Resistance Training
Conditions
Keywords
alzheimer disease, elderly, exercise, fall risk
Brief summary
Interventional study to show the effects of strength exercise on fall risk in elderly with Alzheimer's disease
Interventions
PROCEDUREStrength exercise
Strength exercise protocol for upper and lower limbs, using weights and elastic bands
OTHERUsual treatment
The usual treatment is based on activities to enhance brain functions: attention, memory, executive functions, language and orientation.
Sponsors
University of Jaén
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* accept to participate in the study, through informed consent * subjects aged 60 or over with medical diagnosis of Azlheimer´s disease * minimal physical and mental state to perform the cognitive tests and strength exercise routine
Exclusion criteria
* Neurodegenerative disease other than Alzheimer's disease * Suffering from serious somatic or psychiatric illnesses * Patients who have practiced strength exercise regularly
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline Short physical performance battery (SPPB) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | Informs about fall risk and mobility Score: 0-12 High score means better result |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline Lawton Instrumental Activities of Daily Living Scale (IADL) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | This tool gives us information about performance in activities of daily living Score: 0-8 High score means better result |
| Change from baseline Quality of life Alzheimer Disease (QoL-AD) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | Through this test we can know the level of quality of life of users who suffer from this disease Score: 0-52 High score means better result |
| Change from baseline FRAIL test at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | This rapid test allows to determine the state of frailty of older people Score: 0-5 High score means worst result |
| Change from baseline Mini Mental State Examination (MMSE) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | This test gives us information about the cognitive performance of the participants Score: 0-30 High score means better result |
| Change from baseline Activities specific balance confidence scale (ABC scale) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | This questionnaire allows to measure the balance of a person Score: 0-100% High percentage means better result |
| Change from baseline Manual dynamometry at 1,2,3 and 6 months | Baseline, 1, 2, 3 and 6 months (3 months after intervention) | This test allows to quantify force an individual presents in a simple way Score: 0-∞ High score means better result |
| Modified Borg scale | 3 times/week during strength exercises sessions | In this way we can measure the level of perceived exertion during the intervention with strength exercise Score: 0-10 High score means more fatigue |
| Change from baseline One Maximum repetition strength test (1 MR) at 1,2,3 and 6 months | Baseline, 1 , 2 , 3 and 6 months (3 months after intervention) | Allows you easily to assess maximum strength Score: 0-∞ High score means more strength level |
| Change from baseline Neuropsychiatric Inventory (NPI-Q) at 3 and 6 months | Baseline, 3 and 6 months (3 months after intervention) | This tool allows to specify the neuropsychiatric symptoms patients present Score: 0-36 High score means worst result |
Countries
Spain
Outcome results
None listed