Hypoxia
Conditions
Keywords
surgery, airway, hypoxia prevention, oxygen insufflation
Brief summary
The purpose of this project is to evaluate the efficacy of oxygen insufflation (continuous oxygen flow) to keep oxygen saturation (oxygen levels measured with a pulse oximeter \[finger device used in medicine\]) at 90% or greater in adult patients undergoing microlaryngoscopy surgery.
Detailed description
High flow, low pressure oxygen will be supplied in microlaryngoscopy airway surgery. These procedures are usually performed with jet ventilation (UAB) or intermittent apnea (surgery centers). Jet ventilation provides oxygenation with limited ventilation but come with high risks, such as barotrauma, pneumothorax, mucosa drying, and even death in the most severe cases. Intermittent apnea is a nuisance for the surgeon in that surgical time is often interrupted with having to place the endotracheal tube whenever the patient's oxygen saturation levels fall. The solution is oxygen insufflation, which will give extended oxygenation times for the surgeon to operate without the inherent risks associated with jet ventilation. During the procedure, oxygen tubing will be connected to the surgeon's laryngoscope instead of the jet ventilation tubing. Oxygen flows of 15 L/min will be administered through the laryngoscope to the posterior oropharynx. Endotracheal tube will be placed if oxygenation deemed insufficient due to oxygen saturations of \<90%. Endotracheal tube will be intermittently placed to check and correct carbon dioxide levels.
Interventions
DEVICEInsufflator oxygen tubing
high flow, low pressure oxygen with pressure relief valve and luer Lock connections delivered at 15 L/min through surgeon's laryngoscope.
Sponsors
University of Alabama at Birmingham
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DEVICE_FEASIBILITY
Masking
NONE
Intervention model description
There will be a single group of participants in which all receive oxygen insufflation to see if oxygen insufflation is adequate in microlaryngoscopy airway surgery.
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* adult patients undergoing microlaryngoscopy surgery without a tracheostomy
Exclusion criteria
* patients who have a tracheostomy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| High flow, low pressure oxygen can increase apneic oxygenation time during airway procedures | 30-60 minutes | 15 liters per minute of oxygen will be administered to the posterior oropharynx. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Degree of hypercapnia experienced by participants | 30-60 minutes | Measurement will be taken by intermittent ventilation by placing an endotracheal tube |
| Participants That Maintain Adequate Oxygenation at 90% or Greater | 30-60 minutes | Pulse oximetry will be used to measure oxygenation status |
Outcome results
None listed