Validation of PVI in Tidal Volume Challenge Test
Conditions
Keywords
tidal volume challenge,Plethysmography variability index,Fluid responsiveness
Brief summary
Determine the ability of changes in Plethysmographic Variability Index during tidal volume challenge to predict fluid responsiveness
Detailed description
The change of Plethysmographic Variability Index after tidal volume challenge as a predictor of fluid responsiveness, confirmed with the change of SVV using Flotrac advance cardiac output monitor. To determine whether the patient is fluid responder, Fluid challenge will be performed afterwards to confirm the patient's fluid responsiveness. We also aim to calculate the least significant change for Plethysmographic Variability Index and Philips PPV system.
Interventions
None listed
Sponsors
National Taiwan University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Inclusion: Patients undergoing elective major surgery (estimated \> 2-hr) with general anesthesia and mechanical ventilation in supine position Exclusion: 1. BMI \< 18.5 or \>30 kg/m2 2. Pregnant patient 3. Allergy to starch solution 4. estimated glomerular filtration rate\< 60
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The predictive ability of change in Plethysmographic Variability Index after Tidal volume challenge to predict fluid responsiveness | 20 minutes | The change in value of Plethysmographic Variability Index after increasing VTE from 6 ml/kg to 8 ml/kg. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Least significant change for Massimo PVI and Philips PPV | 20 minutes | Calculate the least significant change for Massimo PVI and Philips PPV using data acquired from our electronic system |
Countries
Taiwan
Contacts
Primary ContactChun-Yu Wu
Outcome results
None listed