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USI and/or DO in Women With Cystocele Before and After Cystocele Repair

Prevalence of Urodynamic Stress Incontinence and/or Detrusor Overactivity in Women With Cystocele and the Changes of Continence Function After Cystocele Repair

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04978714
Enrollment
483
Registered
2021-07-27
Start date
2010-11-01
Completion date
2020-10-31
Last updated
2021-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Detrusor Overactivity, Urodynamic Stress Incontinence

Keywords

Urodynamic stress incontinence, Detrusor Overactivity, Cystocele

Brief summary

The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress incontinence and/or detrusor overactivity in women with ≥ stage II cystocele and the changes of incontinence function after cystocele repair.

Detailed description

Between November 2010 and October 2020, all women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair were reviewed. Those women who had complete data of preoperative and postoperative 3-month follow-up urodynamic data were excluded from this study. Urodynamic stress incontinence was diagnosed by the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction. Detrusor overactivity was defined as the occurrence of involuntary detrusor contractions during filling cytometry. STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression tests were used for statistical analysis as appropriate. A p \< 0.05 was considered as statistically significant.

Interventions

Fascial repair for endopelvic fascia and anterior colporrhaphy

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Women with ≥ stage II cystocele * Received cystocele repair * Complete urodynamic study before and after surgery

Exclusion criteria

* Incomplete data * Chronic infection * Recurrent surgery for cystocele

Design outcomes

Primary

MeasureTime frameDescription
Urodynamic stress incontinenceNovember 2010 and October 2020the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction
Detrusor overactivityNovember 2010 and October 2020the occurrence of involuntary detrusor contractions during filling cytometry

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026