Blood Flow Restriction
Conditions
Keywords
resistance training, muscle function, quadriceps, eccentric strength, vertical jump, muscle quality, muscle hypertrophy, eccentric training
Brief summary
The study will determine the effects of adding blood flow restriction to eccentric training to assess whether this increases the improvements of muscle strength and size.
Detailed description
Subjects will be randomly assigned to two groups: an eccentric only resistance training group or an eccentric training plus blood flow restriction group. Subjects will train at a moderately low intensity on a multiple-joint eccentric device. Those in the blood flow restriction will wear blood flow restriction cuffs on their upper thighs to reduce blood flow during the brief protocol. The training session will occur twice per week and will last \ 5 minutes, including a one minute warm up, a one minute cool down and a three minute workout phase. The training program will last 7 weeks. Testing will be conducted at baseline (following a one session familiarization), 4 weeks and after the end of the 7 week training period. Assessments will focus on muscle strength, function, and morphology (size).
Interventions
OTHERExercise
The interventions are a form or exercise, specifically resistance exercise.
OTHEREccentric plus blood-flow restriction
Eccentric plus blood-flow restriction
Sponsors
Utah State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)
Masking description
The person assessing the outcome measures will be blinded to the group designation of the subjects.
Intervention model description
Two group, randomized parallel group design.
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-30 years of age * currently engaged in some form of resistance training between 1-3 times per week * must have been training aerobically, but no more than 3 hours a week for the past six months
Exclusion criteria
* Must not have had any surgery of the lower limbs within the past 1 year period * Must not have any neuromuscular disorder (e.g., Muscular dystrophy etc.) * \< 76 inches tall (in order to fit on the training machine) * Maximal strength of \< 725 lbs for the eccentric training device * If any of the subjects are pregnant or plan to be pregnant in the duration of the protocol. For those randomized to the BFR group, if any of the subject's thighs are too large for the BFR cuffs (greater than 68 cm).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Eccentron maximal muscle strength | 7 weeks | Eccentric muscle strength will be assessed via Eccentron (BTE Technologies, Inc., USA), an seated isokinetic dynamometer. |
| Local muscle hypertrophy | 7 weeks | Muscle size changes of the quadriceps muscle measured an ultrasound device (GE NextGen LOGIQ, Tampa, Florida, USA). |
| Muscle mass | 7 weeks | dual energy x-ray absorptiometry device (DEXA) the Hologic Horizon W Dual X-ray absorptiometry (Hologic Canada ULC, Mississauga, ON, Canada) will be used to assess appendicular (lower body) mean mass. |
| Muscle function | 7 weeks | Vertical jump height will assess 3 maximal countermovement attempts on a jump mat (Just Jump Technologies, Huntsville, AL, USA) that measures jump height based on flight time. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscle soreness | 7 weeks | local muscle soreness will be assessed throughout the duration of the intervention period using a Wagner force algometer. |
Countries
United States
Outcome results
None listed