Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery

Using Machine Learning to Predict Acute Kidney Injury Requiring Renal Replacement Therapy After Cardiac Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04977687

Enrollment

2108

Registered

2021-07-27

Start date

2020-09-01

Completion date

2021-01-01

Last updated

2021-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, Machine Learning, Prediction Models, Renal Replacement Therapy

Brief summary

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication which may result in adverse impact on short- and long-term mortality. The researcher here developed several prediction models based on machine learning technique to allow early identification of patients who at the high risk of unfavorable kidney outcomes. The retrospective study comprised 2108 consecutive patients who underwent cardiac surgery from January 2017 to December 2020.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age over 18 years who underwent cardiac surgery

Exclusion criteria

* data miss greater than 10%

Design outcomes

Primary

Measure	Time frame	Description
patients required renal replacement therapy	14 days	The primary outcome was patients with the requirement for acute dialysis within 14 days after cardiac surgery. Renal replacement therapy is recommended for patients with severe acute kidney injury as well as hemodynamic instability or severe electrolyte disturbances (e.g. blood potassium \> 6) or acid-base balance disturbances (e.g. H value less than or equal to 7.15). Prior to the start of renal replacement therapy, the investigator invited a consultation with the nephrology department to assess the condition

Countries

China

Outcome results