Phobia
Conditions
Keywords
phobia, VR
Brief summary
To explore the efficacy of drugs combined with virtual reality exposure therapy in the treatment of phobias compared with single drug treatment.
Interventions
DEVICEvert
On the basis of sertraline drug treatment, phobia patients were given 2d/times from the 5th week, each 35-45min VR exposure treatment, 15 times as a course of treatment.
DRUGSertraline
Sertraline was given as a single drug, with an initial dose of 50 mg/d, and gradually increased to the maximum dose of 200 mg/d after 2 weeks. The treating physician will determine the specific dose adjustment according to the patient's condition.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Meet the diagnostic criteria for phobias in DSM-IV. * Age from 18 to 45 years old. * Graduated from junior high school or above. * No serious physical disease, no serious visual impairment, and no family history of mental illness.
Exclusion criteria
* Exclude other psychiatric diagnosis and treatment history.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the level of anxiety | 3 months | the score of Hamilton anxiety scale, the minimum and maximum values are 0 and 56, and higher scores mean a worse outcome. |
| heart rate of the patients | 3 months | take the heart rate as a biomarker of fear, the faster heart rate means the participate is more afraid |
Countries
China
Contacts
Primary Contactzheng lin, doctor
Outcome results
None listed