Infective Endocarditis
Conditions
Brief summary
This was a retrospective observational study of consecutive cases of definite or possible infective endocarditis (IE) as per the modified Duke criteria between January 2008 and December 2015, which was performed at the Second Affiliated Hospital of Zhejiang University, School of medicine (SAHZU), a tertiary care referral hospital located in East China.
Detailed description
Infective endocarditis (IE) is a rare but life-threatening serious disease that still has a high mortality, even in developed countries. The objective of this study was to evaluate the clinical presentations, treatment and outcomes of IE patients in a tertiary hospital in East China over an 8-year period. This was a retrospective observational study of consecutive cases of definite or possible IE as per the modified Duke criteria between January 2008 and December 2015.
Interventions
OTHERno intervention
no intervention
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with a clinical diagnosis of infective endocarditis.
Exclusion criteria
* Patients did not meet the modified Duke criteria.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complications (neurological events, systemic embolism, and congestive heart failure) of infective endocarditis | During the hospitalization, average of 1 months | 1. A neurological event was defined as symptomatic or asymptomatic stroke, hemorrhage, or encephalopathy. 2. Systemic embolization was defined as an embolic event outside of the central nervous system. 3. Congestive heart failure was defined as with class III, or IV heart failure and an ejection fraction of 40% or less. |
| Mortality | During the hospitalization, average of 1 months | Patients dead or moribund before discharge |
Outcome results
None listed