Coronary Disease
Conditions
Keywords
Autonomic Nervous System, Fluid Therapy, Heart Rate, Exercise
Brief summary
The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes. However, the influence of fluid replacement when administered during and after exercise on cardiac autonomic modulation with autonomic alterations known as the coronary arteries remain poorly understood. The aim of the study was to evaluate and compare whether different hydration strategies are able to promote acceleration of the recovery of autonomic modulation in individuals with coronary artery disease undergoing aerobic exercise. This study is a cross-over clinical trial, which will be developed based on an experimental procedure performed in four stages. A total of 31 individuals will be recruited in this study and will perform four standardized cardiovascular rehabilitation (CR) sessions. The participants will perform CR with mineral water intake in phase three and four. In phase three, the consumption will be done a quantity of water predetermined by the evaluator, based on the loss of body mass measured in the second session. In phase four, hydration will be carried out in an uncontrolled manner, according to the desire to drink water during the protocol.
Interventions
OTHERTreadmill aerobic exercise without water intake
The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 60 minutes of recovery at the supine position.
OTHERTreadmill aerobic exercise with water intake of a predetermined amount.
The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position.
OTHERTreadmill aerobic exercise with water intake according to the desire to drink
The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position.
Sponsors
Universidade Estadual Paulista Júlio de Mesquita Filho
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
45 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Men with coronary heart disease ischemia, over 45 years * At least three months of cardiovascular rehabilitation
Exclusion criteria
* Smokers, alcoholics * Uncontrolled metabolic disease (eg, uncontrolled diabetes and thyroid diseases) * Abnormal hemodynamic responses during exercise such as disproportionate increase / fall of heart rate and / or blood pressure to low / high levels of load * Myocardial ischemia and / or severe ventricular arrhythmias during the exercise test
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate variability | up to six months | Linear indices of heart rate variability in the time domain (SDNN, rMSSD). |
Countries
Brazil
Contacts
Primary ContactLorena Santos, BPT
Backup ContactLuiz Carlos Vanderlei, PhD
Outcome results
None listed