Bilateral Knee Osteoarthritis
Conditions
Keywords
Bilateral knee arthroplasty, Gait analysis, Smart-phone
Brief summary
Total knee arthroplasty is a well-known treatment of the end-stage osteoarthritis of the knee. In the case of bilateral end-stage knee osteoarthritis, both of the knees need total knee arthroplasty. Bilateral total knee arthroplasty could be performed simultaneously or staged according to the preference of the patients. Simultaneous total knee arthroplasty is defined as the replacement of both knees in a single surgery. The major advantage of simultaneous total knee arthroplasty this surgery is that it requires only one hospital stay and a rehabilitation period to recover both knees, but higher blood transfusion rates and thromboembolism risk are still major concerns. Therefore, in this comparative study, smart-phone based gait analysis and patient-reported functional outcomes are evaluated in patients undergoing simultaneous and staged total knee arthroplasty, at 3, 6, and 12 months postoperatively
Detailed description
Patients with bilateral end-stage knee osteoarthritis will be included in the current study. Bilateral total knee arthroplasty will be performed simultaneously or staged according to the preference of the patients. We will have two groups: staged total knee arthroplasty and simultaneous total knee arthroplasty groups. The patients will be evaluated preoperatively and at 3, 6, and 12 months postoperatively, with knee scores (Knee Society Scores and Knee Injury and Osteoarthritis Outcome Score), life quality (SF-12), and smart-phone based gait analysis. All data will be calculated as mean and standard deviation values. The Student's t-test will be used for statistical analysis of the patient data. Statistical calculations will be performed using SPSS vn.22.0 software (IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY, USA).
Interventions
PROCEDURETotal knee arthroplasty
Bilateral surgery in one arm and staged surgery in another arm during total knee arthroplasty
Sponsors
Gulhane Training and Research Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
Clinical diagnosis of bilateral primary knee osteoarthritis Age 55 to 85 years Must be able to walk without support
Exclusion criteria
Rheumatological joint diseases Previous knee surgery Neuromuscular diseases Unilateral knee osteoarthritis Insufficiency of knee collateral ligaments.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| smart-phone based gait analysis | Change from preoperative gait analysis at 3rd month gait analysis | Gait analysis (The gait velocity, step time (ST), step length (SL), cadence, step length symmetry and step time symmetry) is made using the Gait Analyzer version 0.9.95.0 (Control One LLC, NM, USA) smartphone application |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Knee functional scores | Change from preoperative Knee Society Scores (KSS) at 3rd month Knee Society Score (KSS) | Knee Society Score (KSS) (has two different subscale : Knee and Function 100-80: Excellent 79-70:Good 69-60:Fair below 60:Poor ) |
Countries
Turkey (Türkiye)
Contacts
Primary ContactDeniz Cankaya, Assoc.Prof.
Backup ContactAnıl Ozgur, MD
Outcome results
None listed