Alertness, Cognitive Performance, Fatigue, Mental, Mood, Motivation
Conditions
Keywords
alertness, mental fatigue, coffeeberry, coffee fruit
Brief summary
The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance. Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.
Interventions
DIETARY_SUPPLEMENTCherry-flavored still beverage
10 oz bottle
OTHERPlacebo cherry-flavored still beverage
10 oz bottle
Sponsors
PepsiCo Global R&D
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
17 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Are older than 17 and under 50 years of age * Self-report of good health
Exclusion criteria
* Using any prescription medication including birth control * Report hypersensitivity to caffeine * Have visual impairment that cannot be corrected with glasses or contact lenses * Report any food allergies * Self-reported excessive leisure time physical activity (\> 7 strenuous bouts per week) * the presence of current gastrointestinal, sleep, or psychiatric disorder, * Report pregnancy/lactation, illegal drug use, smoker * failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks. * Participation in another clinical trial within past 30 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognition score | Change from baseline to 60 and 120 min post-consumption. Higher test scores are better. | Objective Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) for word and picture presentation and recall, serial 3 and 7 subtraction, Rapid Visual Information Processing (RVIP). |
| Fatigue score | Change from baseline to 60 and 120 min post-consumption. Lower fatigue score is better. | Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) |
| Alertness score | Change from baseline to 60 and 120 min post-consumption. Higher alertness score is better. | Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS) |
| Calmness score | Change from baseline to 60 and 120 min post-consumption. Higher calmness score is better. | Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS) |
| Contentedness score | Change from baseline to 60 and 120 min post-consumption. Higher contentedness score is better. | Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS) |
| Motivation score | Change from baseline to 60 and 120 min post-consumption. Higher motivation score is better. | Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS) |
| Energy score | Change from baseline to 60 and 120 min post-consumption. Stronger feelings of mental and physical energy are better. | Subjective mental and physical state energy and fatigues scales (EFS-State Scale). Composite scores range from 0 to 300 mm, from feelings of no energy to strongest feelings of energy during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) |
Countries
United States
Outcome results
None listed