Tissue Oxygen Saturation for Esophagectomy

Tissue Oxygen Saturation During Gastric Tube Reconstruction With Cervical Anastomosis for Esophagectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04973046

Enrollment

Registered

2021-07-22

Start date

2020-11-01

Completion date

2021-04-30

Last updated

2021-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anastomotic Leak, Esophageal Neoplasms, Esophagostomy Complication, Oxygen Deficiency

Keywords

Esophagectomy, Tissue oxygen saturation, Gastric tube, Anastomotic leakage

Brief summary

Tissue oxygen saturation monitoring was a useful indicator of blood flow insufficiency in the gastric tube leading to anastomotic leakage during radical esophagectomy.

Detailed description

One cause of anastomotic leakage after radical esophagectomy is blood flow insufficiency at the cervical anastomosis site. . Eighteen patients, who underwent radical esophagectomy with gastric tube reconstruction, were studied. The regional tissue oxygen saturation (rSO2) was measured at the tip (point pre 0) and 2, 4, and 6 cm on the anal side of the tip (point pre 1, pre 2, and pre 3, respectively) before the gastric tube was raised to the cervical site through the retrosternal route. After that, rSO2 was measured at the tip, 2 and 4 cm on the anal side of the tip (points post 0, post 1, and post 2), the actual anastomotic site (point AN), and the chest skin as an indicator of whole-body oxygenation . The relationship between rSO2 scores and the rate of anastomotic leakage was determined.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients who underwent esophagectomy with gastric tube reconstruction from November 2020 to March 2021.

Exclusion criteria

* Patients who underwent esophagectomy with jejunum or colon reconstruction. patients who underwent two-stage operation.

Design outcomes

Primary

Measure	Time frame	Description
The tissue oxygen saturation score of gastric tube during esophagectomy	During surgery	We measured the tissue oxygen saturation (0% - 99%) of several parts of gastric tube during esophagectomy with a use of tissue saturation monitor ''toccare''.

Secondary

Measure	Time frame	Description
The rate of anastomotic leakage	1month after surgery	We investigated the rate of anastomotic leakage in the cervical site (0% - 100%).

Countries

Japan

Outcome results