Capsule Endoscopy
Conditions
Keywords
Capsule endoscopy
Brief summary
The aims of this study are to evaluate the effect of early drinking water after the capsule ingestion on the gastrointestinal transit and image quality of capsule endoscopy.
Detailed description
Capsule endoscopy has been a significant technologic advancement that has allowed the direct examination of mucosa throughout the entire small intestine in a noninvasive fashion; and it has become the primary technique for imaging the small bowel. However, as imaging time is limited to about 8 hours, a prolonged transit of the capsule endoscope in the stomach may result in an incomplete small bowel transit (i.e. failure of the capsule to reach the cecum). Delayed transit time of stomach may be responsible for the failure of capsule endoscopy to visualize the distal portions of the small bowel, and potentially may result in the inability to identify small-bowel pathology in these areas. Previous study showed that drinking water might improve completion rate of capsule endoscopy. And bowel preparation of clear liquids may improve image quality of small bowel mucosa. The aim of this study was to assess the effect of drinking water on the transit time，completion rate and image quality of capsule endoscopy.
Interventions
OTHERdrinking water group
Those randomized to drink water group were asked to drink 200 mL colorless water every 10 minutes, starting at the time of capsule ingestion until three times in total.
OTHERcontrol group
Those randomized to control group were asked not to drink extra water after capsule ingestion.
Sponsors
Shandong University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Patients aged 18-80 years undergoing capsule endoscopy
Exclusion criteria
1. Patients with suspected intestinal obstruction, intestinal diverticulum, stricture or fistula 2. previous gastric or small-bowel surgery 3. pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| gastric transit time | 3 months | the time between the first gastric image and the first duodenal image |
| small-bowel transit time | 3 months | the imaging time of capsule endoscopy in the small bowel |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| complete examination rate of the small bowel | 3 months | the percentage of patients with complete examination of the small bowel in each group |
| image quality | 3 months | The scale was based on the uncovered image area percentage (0, 0%-20%; 1, 20%-40%; 3, 60%-80%; 4, 80%-100%). The image quality was based on the mean of 5-min scores and higher scores mean a better outcome. |
| diagnostic yields | 3 months | Clinical diagnoses made by the capsule endoscopy were recorded for each patient. |
Countries
China
Contacts
Primary ContactXiuli Zuo, MD, PhD
Outcome results
None listed