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Suicide Prevention by Empowering Adolescents in Pakistan (SEPAK)

Suicide Prevention by Empowering Adolescents in Pakistan (SEPAK): A Feasibility Study for Research Capability and Trial Readiness in Pakistan

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04969718
Acronym
SEPAK
Enrollment
1350
Registered
2021-07-21
Start date
2021-07-01
Completion date
2022-08-30
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Self-harm

Keywords

self-harm, suicide prevention, school-based intervention, Pakistan

Brief summary

Self-harm is now seen as an epidemic affecting young people across the world and particularly in low and middle-income countries (LMIC) such as Pakistan. Young people in Pakistan often come across many troubles such as mental health and family problems, stress at school and social and economic inequalities. A youth suicide prevention programme is needed in Pakistan. Such programme will be based on secondary schools (where most young people are) and will support schools to work together with many public agencies to tackle the full range of troubles that young people face. Our main research aim is to work together with multiple stakeholders to culturally adapt and test the feasibility of three SEPAK interventions to prevent suicide among students in secondary schools in Pakistan (aged 12 to 17 years).

Detailed description

There will be two research phases. In the first phase, 1. Four preventative interventions will be selected and translated after reviewing the international literature on youth suicide prevention programmes (e.g. SEYLE trial in Europe); 2. Focus groups will be undertaken with multiple stakeholders (students, teachers/staff at secondary schools, parents and health professionals) to decide on adaptations needed to the four selected interventions; 3. Adapted versions the four preventative SEPAK interventions will be produced after incorporating the modifications recommended by the focus groups with stakeholders. In the second phase, the feasibility and acceptability of the four preventative SEPAK interventions will be examined in 4 secondary schools (each site) and one control group (each site) across 8 cities in Pakistan. The four preventative interventions will involve i. Delivering workshops for students at secondary schools to raise awareness on mental health and stresses that students face. ii. Training school teachers/workers to act as facilitators and identify troubled students iii. Training parents to act as facilitators and identify and support troubled young people iv. Training of health professionals who work with young people to systematically use cut-off scores of established psychometric tools for referring young people to mental and social care services. Six posters on mental health awareness will display in the classrooms of the school allocated to the control group.

Interventions

OTHERLEADS Plus educational posters

This intervention covers depression and its symptoms, the link between depression and suicide, the risk and protective factors associated with suicide, the warning signs of suicide, seeking help and overcoming barriers to seeking help, and school and community suicide prevention resources. Six educational posters will also be displayed in class rooms

OTHERQuestion, Persuade, and Refer (Teachers) Plus educational posters

It is a manualised programme for gatekeepers, originally developed in the USA which to train teachers/school staff to identify the suicide risk in students and encourage students at risk of suicide to seek professional help. Six educational posters will also be displayed in classrooms.

OTHERScreening by Professionals programme plus educational posters

This is an indicated or selective intervention which is based on students' responses to the baseline questionnaires. Participating health professionals review students' responses to the questionnaires used in the study and students whose scores meet pre-established cutoff points will be invited to participate in a professional mental health clinical assessment and if needed, referred to clinical services. Six educational posters will also be displayed in classrooms.

OTHEReducational posters

Six educational posters will be displayed in all schools in this cluster.

OTHERQuestion, Persuade, and Refer (Parents) Plus educational posters

It is a manualised programme for gatekeepers (parents), originally developed in the USA which to train parents to support the young people at risk of suicide. Six educational posters will also be displayed in classrooms.

Sponsors

University of Manchester
CollaboratorOTHER
Pakistan Institute of Living and Learning
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

for students: 1. age 12 - 17 years 2. the school authority agrees for the student to participate; 3. both parents and students willing to participate.

Exclusion criteria

students: 1. the school authority refuses for the student to participate; 2. the adolescents attend a specialist and/or independent or private school; 3. the parents of students in a participating school, or the students themselves, have refused to sign the consent document. Parents/guardians Parents/guardians are eligible to participate if they meet all the following criteria: 1. caring for pupils aged 12-17 years; 2. the school authority agrees for the school to participate; 3. willing to participate in the study; 4. willing for pupils they care for to participate in the baseline and post-intervention assessments. If parents/guardians meet the following

Design outcomes

Primary

MeasureTime frameDescription
Feasibility of undertaking a trial of the interventionChange from baseline to 1-month post baselinerecruitment rate of the trial
Therapy logChange from baseline to 1-month post baselineacceptability of the interventions that will be evident from the attendance of participants in each session on a therapy log

Secondary

MeasureTime frameDescription
Kessler Psychological Distress ScaleChange in scores from baseline to outcome (1-month post baseline)This will use to measure psychological distress. It's a 10 item scale measuring emotional states with a 5 level response scale. Minimum score is 10 and a maximum score is 50. Low scores indicate low levels of psychological distress and high scores indicate high levels of psychological distress.
Beck Scale for Suicidal Ideation (BSSI)Change in scores from baseline to outcome (1-month post baseline)This scale is a 19-items instrument that evaluates the presence and intensity of suicidal thoughts in a week. Minimum total score is 0 and maximum total score can be 38. Higher scores indicate worse outcome.
The Global school-based student health survey (GSHS)Change in scores from baseline to outcome (1-month post baseline)The is a self-administered questionnaire and covered ten key topics: alcohol use, dietary behaviors, drug use, hygiene, mental health, physical activity, protective factors, sexual behaviors, tobacco use, and violence and unintentional injury
Client Service Receipt InventoryChange in scores from baseline to outcome (1-month post baseline)We will collect information on the use of health services (including the informal sector such as faith healers/Imams)
Client Satisfaction QuestionnaireScores reported by the participant on the scale after intervention at 1-month post baselineParticipant satisfaction with services will be assessed using the Client Satisfaction. The total score ranges from 8 to 32. Higher scores indicate higher level of satisfaction. Questionnaire (CSQ)
Euro-Qol (EQ-5D-5L)Change in scores from baseline to outcome (1-month post baseline)A standardised instrument to measure health status and associated population utility weights. It consists of a self-report questionnaire covering five dimensions of health (mobility, self-care, usual activities, pain/ discomfort and anxiety/ depression)
Deliberate Self-Harm InventoryChange in scores from baseline to outcome (1-month post baseline)DSHI will be used to collect information about episode of self-harm. Minimum score is 0 and maximum score is 34. Higher total score indicate the higher intensity of the problem.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026