Cervical Myelopathy
Conditions
Keywords
Cervical Myelopathy, Axial Pain, Electroencephalogram Analysis
Brief summary
The characteristic of axial pain and EEG analysis of patients after laminoplasty
Detailed description
The characteristic of axial pain after open-door laminoplasty in patients with degenerative cervical spine myelopathy and the correlation with electroencephalogram analysis: a prospective cohort study.
Interventions
None listed
Sponsors
Peking University Third Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* Age: 18\ 70 years. * Diagnosed as degenerative cervical spine myelopathy. * Must receive C3-C7 open-door laminoplasty. * Agree to join this study and sign the informed consent.
Exclusion criteria
* Severe cervical spine kyphosis. * Cervical spine radiculopathy. * Laminoplasty with fusion. * Cervical spine anterior column lesion because of tumor, trauma or infection. * Severe osteoporosis. * Morbid obesity. * patients with mental disorder. * Pregnancy. * History of infection within last 3 months. * Severe nervous system disease. * Abnormal laboratory report of liver function, kidney function and hematologic system. * Poor compliance. * Patients with other surgical contraindications. * Patients with intemperance or taking drugs. * Patients who joined other study within the last 3 months. * Patients with a chief complaint of neck pain (VAS score ≥3 points). * Left handedness.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Electroencephalogram analysis | 3 months after surgery. | Electroencephalogram analysis (focus on the gamma oscillation at prefrontal cortex) at 3-month follow-up. |
| Visual analogue scale for axial pain | 3 months after surgery. | Visual analogue scale for axial pain before operation and at 3-month follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Outcome of cervical spine function | 3 months after surgery. | Neck Disability Index score before operation and at 3-month follow-up |
| Quality of life outcome | 3 months after surgery. | SF-36 score before operation and at 3-month follow-up |
| Psychological measures | 3 month after surgery. | Beck Depression Inventory score before operation and at 3-month follow-up |
| Trail Making Test | 3 month after surgery. | Trail Making Test before operation and at 3-month follow-up |
Countries
China
Contacts
Primary ContactFeifei Zhou, M.D.
Outcome results
None listed