Isthmic Spondylolisthesis
Conditions
Keywords
Isthmic Spondylolisthesis, Spinopelvic parameter, Clinical symptom, Pelvic incidence, Lumbar lordosis
Brief summary
This was a retrospective study.PI and LL greatly influence IS and its progression. However, relationships between the spinopelvic parameters and clinical symptoms of patients with IS were not fully investigated in previous studies. Investigators hypothesized that spinopelvic parameters might be related to the clinical symptoms of IS patients. Therefore, the purpose of the present study was to investigate whether differences in spinopelvic parameters, especially spinopelvic alignment, may be associated with the clinical symptoms of low-grade IS patients.
Detailed description
Isthmic spondylolisthesis (IS) is one of the most common types of spondylolisthesis, and spinopelvic parameters are closely related to the clinical symptoms of spinal diseases. In this study, investigators attempted to investigate the relationship between spinopelvic parameters and clinical symptoms of patients with low-grade (Meyerding grade I-II) isthmic spondylolisthesis (IS). A total of 120 patients with low-grade IS and 106 asymptomatic adults were included in this study. Sex, age and body mass index (BMI) were also collected. Various spinopelvic parameters were evaluated in whole-spine standing-position X-rays. The following spinopelvic parameters were measured: pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT) and lumbar lordosis (LL). The clinical symptoms of the IS patients were assessed with the Japanese Orthopaedic Association (JOA) score and the visual analogue scale (VAS). Investigators compared spinopelvic parameters between the asymptomatic adults and the IS patients. Additionally, investigators investigated correlations between spinopelvic parameters and clinical symptoms.
Interventions
RADIATIONPI-LL
The pelvic parameters were collected including PI, pelvic tilt (PT), sacral slope (SS) and LL ,and compared between IS patients and the AS group. Besides, spinopelvic malalignment was defined as an absolute value of PI-LL greater than 10.In the IS group,the clinical symptoms were assessed with the Japanese Orthopaedic Association (JOA) score and the visual analogue scale (VAS). We compared spinopelvic parameters between the asymptomatic adults and the IS patients. Additionally, we investigated correlations between spinopelvic parameters and clinical symptoms.
Sponsors
Peking University Third Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
54 Years to 76 Years
Healthy volunteers
Yes
Inclusion criteria
* isthmic spondylolisthesis subjects had spondylolisthesis at L4 or L5 (Meyerding grade I-II) with whole-spine standing lateral images
Exclusion criteria
* spondylolisthesis of other types (Degenerative, dysplastic, etc.); * Lumbar infection and/or tumor diseases; * A previous history of lumbar fusion surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PI-LL | through study completion, an average of 1 year | pelvic incidence minus lumbar lordosis |
| SS | through study completion, an average of 1 year | sacral slope |
| PT | through study completion, an average of 1 year | pelvic tilt |
| LL | through study completion, an average of 1 year | lumbar lordosis |
| PI | through study completion, an average of 1 year | pelvic incidence |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| VAS | through study completion, an average of 1 year | visual analogue scale |
| JOA | through study completion, an average of 1 year | The Japanese Orthopaedic Association (JOA) |
Countries
China
Outcome results
None listed