Multimodal Imaging Evaluation and Prognostic Analysis of Cardiac Allograft Vasculopathy in Heart Transplantation

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04966988

Enrollment

1000

Registered

2021-07-19

Start date

2021-08-01

Completion date

2026-08-01

Last updated

2021-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Transplant

Brief summary

The aim is to (1) establish a system of multimodal imaging technology; (2) jointly apply multimodal imaging technology to diagnose of cardiac allograft vasculopathy of heart transplantation; (3) construct a multimodal imaging technology prediction model of adverse events, screening the best non-invasive imaging prediction indicators.

Detailed description

This study will enrolled 1000 HT patients, and the cardiac allograft vasculopathy will be evaluated by multimodal imaging technology. The aim is to (1) establish a system of multimodal imaging technology; (2) jointly apply multimodal imaging technology to diagnose of cardiac allograft vasculopathy of heart transplantation; (3) construct a multimodal imaging technology prediction model of adverse events, screening the best non-invasive imaging prediction indicators.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

• Heart transplantation after January 1st, 2015.

Exclusion criteria

•Age \< 18 years at the time of transplantation; Died within 48 h; Heart-lung transplantation; Heart/kidney transplantation; Re-transplanted within 7 days after transplantation.

Design outcomes

Primary

Measure	Time frame	Description
All cause death	up to 10 year	All cause death after HT was obtained via telephone interview with family members; contact with his/her physicians; or hospital records

Secondary

Measure	Time frame	Description
Major adverse cardiac events	5 year and 10 year	Major adverse cardiac events after the inclusion of the study was obtained via telephone interview with family members; contact with his/her physicians; or hospital records

Contacts

Primary ContactLi Zhang, PhD

zli429@hust.edu.cn18907131488

Backup ContactShuangshuang Zhu, MD

18846032209@163.com15971428009

Outcome results