Acute Abdomen, Refeeding Syndrome
Conditions
Keywords
refeeding syndrome, acute abdominal disease
Brief summary
The refeeding syndrome has been reported without any evidence of prolopnged semistarvation, thus being different from the traditional disease. The investigators wanted to investigate, if sodium infusions could be part of the explanation.
Detailed description
Background: Refeeding syndrome is conventionally connected to start of feeding after prolonged periods of semi-starvation and adaption. However, it is also described in acutely ill patients and in ICU patients without a history of adaption, but sometimes only defined as a drop in p-phosphate without clinical manifestations. The investigators hypothesize, that a positive sodium balance could induce the refeeding-like syndrome (RLS). Method: Consecutive patients for acute, abdominal surgery were included and observed until discharge or up to seven days postoperatively with daily sodium and phosphate balance measurements.
Interventions
Acute surgery for acute abdominal disease
Sponsors
Study design
Eligibility
Inclusion criteria
* age \> 18 yr * ready for acute surgery * able to understand and cooperate.
Exclusion criteria
* pregnancy or breastfeeding * renal insufficiency (p-creatinine\>400 micr mol/l) * re-operations * expected hospital stay \< 24 hours.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| sodium balance | 7 days | correlation between sodium balance and occurrence of the refeeding syndrome |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| plasma phosphate | 7 days | correlation between sodium balance and change in plasma phosphate |
| urinary excretion of phosphate | 7 days | correletion between sodium balance and urinary excretion of phosphate |
| phosphate balance | 7 days | correlation between decline in plasma phosphate and urinary excretion of phosphate |
Countries
Denmark