Preoxygenation With High Flow Nasal Cannula Prolongs Normoxia Time During Induction of Anaesthesia of Bariatric Patients and is Superior to Conventional Preoxygenation With Face Mask.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04965610

Enrollment

100

Registered

2021-07-16

Start date

2021-10-31

Completion date

2022-12-31

Last updated

2021-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Compare Preoxygenation Methods in Bariatric Patients

Brief summary

To compare preoxygenation for induction of general anaesthesia with High Flow Nasal Cannula vs preoxygenation with face mask in patients undergoing bariatric surgery. The hypothesis is that preoxygenation with High Flow Nasal Cannula prolongs normoxia time during induction of anaeshesia and is superior to conventional preoxygenation with face mask. Primary endpoint will be the time during which spO2 \> 92 %. Secondary endpoint will be paCO2.

Interventions

OTHERPreoxygenation with High Flow Nasal Cannula

Preoxygenation for 5 minutes via High Flow Nasal Cannula. After induction of anaesthesia apnoeic oxygenation with HFNC

OTHERPreoxygenation via face mask

Preoxygenation for 5 minutes via face mask. After induction of anaesthesia apnoeic oxygenation with tight fitting face mask

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Masking description

Patients will be divided into two groups by lot.

Intervention model description

Two groups of patients. One receiving preoxygenation via High Flow Nasal Cannula and one group receiving preoxygenation via face mask

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* age over 18 * elective bariatric surgery * written consent

Exclusion criteria

* preexisting lung diseases, congenital heart diseases * known difficult airway * SpO2 \< 92% under ambient air conditions * known diaphragmal hernia * clinically relevant reflux

Design outcomes

Primary

Measure	Time frame	Description
Normoxia time SpO2 > 92%	10 Minutes after induction	Time in which the SpO2 remains \> 92% while patient is apnoeic

Secondary

Measure	Time frame	Description
paCO2	10 Minutes after induction	Increase in arterial CO2 during Apnoea

Contacts

Primary ContactJoachim Jugl

Joachim.Jugl@klinikum-karlsruhe.de004972197467846

Backup ContactFranz Kehl, Prof.

00497219741601

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026